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- Title
Aortic root replacement to treat type A aortic dissection: A comparison of midterm outcomes between composite valve grafts and porcine aortic roots.
- Authors
Salmasi, Mohammad Yousuf; Panda, Abinash; Hartley, Philip; Abdulkhader, Ashiq; Osman, Ahmed; Nienaber, Christoph; Athanasiou, Thanos; Asimakopoulos, George
- Abstract
<bold>Background: </bold>Porcine aortic roots (PAR) have been reported in the literature with acceptable short- and long-term outcomes for the treatment of aortic root aneurysms. However, their efficacy in type A aortic dissection (TAAD) is yet to be defined.<bold>Methods: </bold>Using data from a locally collated aortic dissection registry, we compared the outcomes in patients undergoing aortic root replacement for TAAD using either of two surgical options: (a) PAR or (b) composite valve grafts (CVG). A retrospective analysis was conducted for all procedures in the period from 2005 to 2018.<bold>Results: </bold>A total of 252 patients underwent procedures for TAAD in the time period. Sixty-five patients had aortic root replacements (PAR n = 30, CVG n = 35). Between-group comparisons identified a younger CVG group (50.5 vs 64.5, P < .05) although all other covariates were comparable. Operative parameters were comparable between the two groups. The use of PAR did not significantly impact operative mortality (odds ratio [OR], 0.93; 95% confidence interval [CI], 0.22-3.61; P = .992), stroke (OR, 2.91, 0.25-34.09, P = .395), reoperation (OR, 0.91; 95% CI, 0.22-3.62; P = .882) or length of stay (coeff 2.33, -8.23 to 12.90; P = .659) compared to CVG. Five-year survival was similar between both groups (PAR 59% vs CVG 69%; P = .153) and reoperation was negligible. Echocardiography revealed significantly lower aortic valve gradients in the PAR group (8.69 vs 15.45mm Hg; P < .0001), and smaller left ventricular dimensions both at 6-week and 1-year follow-up (P < .05).<bold>Conclusions: </bold>This study highlights the comparable short- and midterm outcomes of PAR in cases of TAAD, in comparison to established therapy.
- Subjects
AORTIC dissection; AORTIC aneurysms; AORTIC valve; ODDS ratio; CONFIDENCE intervals; PERCUTANEOUS balloon valvuloplasty
- Publication
Journal of Cardiac Surgery, 2020, Vol 35, Issue 8, p1840
- ISSN
0886-0440
- Publication type
journal article
- DOI
10.1111/jocs.14712