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- Title
Caesalpinia ferrea C. Mart. (Fabaceae) Phytochemistry, Ethnobotany, and Bioactivities: A Review.
- Authors
Macêdo, Nair Silva; Silveira, Zildene de Sousa; Bezerra, Antonio Henrique; Costa, José Galberto Martins da; Coutinho, Henrique Douglas Melo; Romano, Barbara; Capasso, Raffaele; Cunha, Francisco Assis Bezerra da; da Silva, Márcia Vanusa; Conforti, Filomena
- Abstract
Caesalpinia ferrea C. Mart., popularly known as "Jucá" or "Pau-ferro", belongs to the Fabaceae family, and is classified as a native and endemic species in Brazil. Numerous studies that portray its ethnobotany, chemical composition, and biological activities exist in the literature. The present study aimed to systematically review publications addressing the botanical aspects, uses in popular medicine, phytochemical composition, and bioactivities of C. ferrea. The searches focused on publications from 2015 to March 2020 using the Scopus, Periódicos Capes, PubMed, Google Scholar, and ScienceDirect databases. The leaves, fruits, seeds, and bark from C. ferrea are used in popular medicine to treat disorders affecting several systems, including the circulatory, immune, cardiovascular, digestive, respiratory, genitourinary, musculoskeletal, and conjunctive systems. The most commonly found chemical classes in phytochemical studies are flavonoids, polyphenols, terpenoids, tannins, saponins, steroids, and other phenolic compounds. The biological properties of the extracts and isolated compounds of C. ferrea most cited in the literature were antibacterial, antifungal, antioxidant, antiproliferative, anti-inflammatory, and healing potential. However, further studies are still needed to clarify a link between its traditional uses, the active compounds, and the reported pharmacological activities, as well as detailed research to determine the toxicological profile of C. ferrea.
- Subjects
BRAZIL; PHYTOCHEMICALS; CAESALPINIA; GOOGLE Scholar (Web resource); LEGUMES; BOTANICAL chemistry; ETHNOBOTANY; PHENOLS; ANTIFUNGAL agents
- Publication
Molecules, 2020, Vol 25, Issue 17, p3831
- ISSN
1420-3049
- Publication type
Article
- DOI
10.3390/molecules25173831