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- Title
Chemical Constituents from the Stems of Tinospora sinensis and Their Bioactivity.
- Authors
Lam, Sio-Hong; Chen, Po-Hsun; Hung, Hsin-Yi; Hwang, Tsong-Long; Chiang, Chih-Chao; Thang, Tran Dinh; Kuo, Ping-Chung; Wu, Tian-Shung
- Abstract
Fifty-seven compounds were purified from the stems of Tinospora sinensis, including three new compounds characterized as a lignan (1), a pyrrole alkaloid (11), and a benzenoid (17), respectively. Their structures were elucidated and established by various spectroscopic and spectrometric analytical methods. Among the isolates, fifteen compounds were examined for their anti-inflammatory potential in vitro. The results showed that several compounds displayed moderate inhibition of N-formyl-methionyl-leucyl-phenylalanine/cytochalasin B (fMLP/CB)-induced superoxide anion generation and elastase release.
- Subjects
LIGNANS; PYRROLES; SUPEROXIDES; ELASTASES; ALKALOIDS; PHENYLALANINE; CYTOCHALASINS
- Publication
Molecules, 2018, Vol 23, Issue 10, p2541
- ISSN
1420-3049
- Publication type
Article
- DOI
10.3390/molecules23102541