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- Title
Calcium-Dependent and Endothelium-Dependent Mechanisms for a Constrictor Response of the Saphenous Vein.
- Authors
T. Tsvyashchenko; Yu. Kudryashov
- Abstract
Acute experiments on narcotized cats (method of venous resistography) were performed to study a constrictor response of the great saphenous vein in the hindlimb to a bolus intravenous injection of norepinephrine and/or angiotensin II. The saphenous vein exhibited an increased or decreased constrictor response to norepinephrine and angiotensin II, which depended on the order of exposure to adverse factors (calcium channel blocker nifedipine and chemical deendothelialization-inducing agent hemoglobin).
- Subjects
VASOCONSTRICTION; SAPHENOUS vein; PHYSIOLOGICAL effects of calcium; ENDOTHELIUM; CATS as laboratory animals; NORADRENALINE; ANGIOTENSIN II
- Publication
Bulletin of Experimental Biology & Medicine, 2009, Vol 147, Issue 2, p170
- ISSN
0007-4888
- Publication type
Article
- DOI
10.1007/s10517-009-0469-3