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- Title
Characteristics of Japanese patients with Leber's hereditary optic neuropathy and idebenone trial: a prospective, interventional, non-comparative study.
- Abstract
With interest we read the article by Ishikawa et al. about an uncontrolled, prospective, intervention study of 51 patients with Leber's hereditary optic neuropathy (LHON) due to the ND4 variant m.11778G>A treated with idebenone (900 mg/day) over 24 weeks [1]. As we mentioned in the present study, the enrolled patients never complained about side effects, such as those that Dr. Finsterer cited, so, we did not mention any side effects. It is not conceivable why patients with elevated transaminases, epilepsy, delirium, or hallucinations, patients with agranulocytosis, and patients with chronic renal failure were excluded.
- Subjects
JAPANESE people; NEUROPATHY; RETINAL ganglion cells
- Publication
Japanese Journal of Ophthalmology, 2021, Vol 65, Issue 2, p313
- ISSN
0021-5155
- Publication type
Editorial
- DOI
10.1007/s10384-021-00827-7