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- Title
Changes in corneal endothelial cell density in patients with normal-tension glaucoma.
- Authors
Sung Cho; Chul Choi; Ki Park
- Abstract
Abstract Purpose To study the changes in corneal endothelial cell density in eyes with normal-tension glaucoma compared with those in controls. Methods A total of 227 subjects in three groups, one each of normal-tension glaucoma and primary open-angle glaucoma patients and one of normal controls, were studied from January 2008 to July 2008 in the Ophthalmology Department of Kangbuk Samsung Hospital. The glaucoma (normal-tension glaucoma and primary open-angle glaucoma) patients included monocular and binocular glaucoma patients. Corneal endothelial cells were examined using a noncontact specular microscope. Results The mean endothelial cell densities in the three groups were as follows: normal-tension glaucoma group, 2696.7 ± 303.9 cell/mm2; primary open-angle glaucoma group, 2370.5 ± 392.3 cell/mm2; and normal group, 2723.6 ± 300.6 cell/mm2. The endothelial cell count was not significantly different between normal-tension glaucoma and normal groups (P = 1.000). Primary open-angle glaucoma patients had significantly lower endothelial cell counts (P P Conclusions There was a significant decrease in corneal endothelial cell density in eyes with primary open-angle glaucoma, but not in eyes with normal-tension glaucoma. Elevated intraocular pressure likely affected the decrease of corneal endothelial cell density in eyes with glaucoma.
- Subjects
CORNEA; ENDOTHELIUM; CELL populations; GLAUCOMA; MONOCULAR vision; BINOCULAR vision disorders; SPECULAR microscopy; INTRAOCULAR pressure; PATIENTS
- Publication
Japanese Journal of Ophthalmology, 2009, Vol 53, Issue 6, p569
- ISSN
0021-5155
- Publication type
Article
- DOI
10.1007/s10384-009-0740-1