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- Title
Interpretation of the Humphrey Matrix 24-2 test in the diagnosis of preperimetric glaucoma.
- Authors
Jin Choi; Na Lee
- Abstract
Abstract Purpose To define the diagnostic precision of the Humphrey Matrix 24-2 test and to determine a clinically applicable cutoff criterion for the inclusion of preperimetric glaucoma. Methods Eyes with preperimetric glaucoma (99 eyes) were defined as having normal standard automated perimetry (SAP) results and a glaucomatous optic nerve head, along with one or more optical coherence tomography (OCT) parameters flagged as Results Pattern standard deviation (PSD) showed a larger area under the ROC curve (AUC) (0.767) than mean deviation (MD) (0.619). A pattern deviation plot (PDP) analysis by modified Anderson criteria showed the highest discriminating power, with a sensitivity of 75.76%, followed by a PSD cutoff value of 3.14 dB (sensitivity, 73.74%). Conclusions FDT Matrix seems to be a valuable clinical tool in the detection of preperimetric glaucoma. Among the parameters of the FDT Matrix, PDP analysis by modified Anderson criteria may provide a reliable cutoff criterion.
- Subjects
GLAUCOMA diagnosis; DIAGNOSTIC equipment for eye diseases; PERIMETRY; OPTIC nerve; OPTICAL coherence tomography; STANDARD deviations
- Publication
Japanese Journal of Ophthalmology, 2009, Vol 53, Issue 1, p24
- ISSN
0021-5155
- Publication type
Article
- DOI
10.1007/s10384-008-0604-0