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- Title
Nausea and vomiting in pregnancy: an association between symptoms and maternal prostaglandin E2.
- Authors
Gadsby, Roger; Barnie-Adshead, Anthony; Grammatoppoulos, Dimitri; Gadsby, Pam; Gadsby, R; Barnie-Adshead, A; Grammatoppoulos, D; Gadsby, P
- Abstract
This study investigated the aetiology of nausea and vomiting in pregnancy (NVP) in primary care using a new methodology. Eighteen women in early pregnancy had 2 blood samples taken in one 24-hour time period, one when they were symptomatic, and another when they were symptom-free. Maternal serum levels of the candidate agents PGE2, IL-1beta, and TNFalpha were measured. The study shows a positive relationship between NVP and maternal serum PGE2 levels in early pregnancy.
- Subjects
COMPARATIVE studies; INTERLEUKIN-1; RESEARCH methodology; MEDICAL cooperation; NAUSEA; PREGNANCY complications; FIRST trimester of pregnancy; RESEARCH; TUMOR necrosis factors; VOMITING; EVALUATION research; DINOPROSTONE
- Publication
Gynecologic & Obstetric Investigation, 2000, Vol 50, Issue 3, p149
- ISSN
0378-7346
- Publication type
journal article
- DOI
10.1159/000010314