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- Title
THE EXPRESSION OF RAR-α, RAR-β AND RAR-γ IN HUMAN KERATINOCYTES AND DERMAL FIBROBLASTS IN VITRO.
- Authors
Rees, J. L.; Redfern, C. P. F.
- Abstract
This article discusses the expression of RAR-α, RAR-β and RAR-γ in human keratinocytes and dermal fibroblasts in vitro. Three classes of retinoic acid receptor, members of the family of steroid/thyroid hormone transcriptional activators, have been identified in the last couple of years and these presumably mediate the biological effects of retinoic acid. Previous results have suggested that primary dermal fibroblast cultures may differ markedly in the expression of RARs. Primary dermal fibroblast lines were established from foreskin, fetal skin and from a variety of sites from patients of age up to 89 years.
- Subjects
KERATINOCYTES; FIBROBLASTS; THYROID hormones; DERMATOLOGY; TRETINOIN; CELLS
- Publication
British Journal of Dermatology, 1990, Vol 123, Issue 6, p827
- ISSN
0007-0963
- Publication type
Article