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- Title
Severe Dengue Epidemics in Sri Lanka, 2003-2006.
- Authors
Kanakaratne, Nalaka; Wahala, Wahala M. P. B.; Messer, William B.; Tissera, Hasitha A.; Shahani, Aruna; Abeysinghe, Nihal; de Silva, Aravinda M.; Gunasekera, Maya
- Abstract
Recent emergence of dengue hemorrhagic fever in the Indian subcontinent has been well documented in Sri Lanka. We compare recent (2003-2006) and past (1980-1997) dengue surveillance data for Sri Lanka. The 4 dengue virus (DENV) serotypes have been cocirculating in Sri Lanka for >30 years. Over this period, a new genotype of DENV-1 has replaced an old genotype. Moreover, new clades of DENV-3 genotype III viruses have replaced older clades. Emergence of new clades of DENV-3 in 1989 and 2000 coincided with abrupt increases in the number of reported dengue cases, implicating this serotype in severe epidemics. In 1980-1997, most reported dengue cases were in children. Recent epidemics have been characterized by many cases in children and adults. Changes in local transmission dynamics and genetic changes in DENV-3 are likely increasing emergence of severe dengue epidemics in Sri Lanka.
- Subjects
SRI Lanka; DENGUE; HEMORRHAGIC fever; EPIDEMICS; VIRUSES; INFECTIOUS disease transmission
- Publication
Emerging Infectious Diseases, 2009, Vol 15, Issue 2, p192
- ISSN
1080-6040
- Publication type
Article
- DOI
10.3201/eid1502.080926