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- Title
Human Immunodeficiency Virus and Leprosy Coinfection: Challenges in Resource-Limited Setups.
- Authors
Kwobah, Charles M.; K.Wools-Kaloustian, Kara; Gitau, Jane N.; Siika, Abraham M.
- Abstract
Mycobacteria leprae(leprosy) and HIV coinfection are rare in Kenya. This is likely related to the low prevalence (1 per 10,000 of population) of leprosy. Because leprosy is no longer a public health challenge there is generally a low index of suspicion amongst clinicians for its diagnosis. Management of a HIV-1-leprosy-coinfected individual in a resource-constrained setting is challenging. Some of these challenges include difficulties in establishing a diagnosis of leprosy; the high pill burden of cotreatment with both antileprosy and antiretroviral drugs (ARVs); medications' side effects; drug interactions; scarcity of drug choices for both diseases. This challenge is more profound when managing a patient who requires second-line antiretroviral therapy (ART). We present an adult male patient coinfected with HIV and leprosy, who failed first-line antiretroviral therapy (ART) and required second-line treatment. Due to limited choices in antileprosy drugs available, the patient received monthly rifampicin and daily lopinavir- /ritonavir-based antileprosy and ART regimens, respectively. Six months into his cotreatment, he seemed to have adequate virological control. This case report highlights the challenges of managing such a patient.
- Subjects
HIV; HANSEN'S disease; HIGHLY active antiretroviral therapy; THERAPEUTICS; HIV infections; LEPROSTATIC agents; VIROLOGY
- Publication
Case Reports in Medicine, 2012, p1
- ISSN
1687-9627
- Publication type
Article
- DOI
10.1155/2012/698513