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- Title
Comparison of the SARS-CoV-2 spike protein ELISA and the Abbott Architect SARS-CoV-2 IgG nucleocapsid protein assays for detection of antibodies.
- Authors
Wadhwa, Ashutosh; Yin, Sherry; Freeman, Brandi; Hershow, Rebecca B.; Killerby, Marie; Yousaf, Anna R.; Lester, Sandra; Mills, Lisa; Buono, Sean A.; Pomeroy, Mary; Owusu, Daniel; Chu, Victoria T.; Tate, Jacqueline E.; Bhattacharyya, Sanjib; Hall, Patricia; Thornburg, Natalie J.; Kirking, Hannah L.
- Abstract
Serologic assays developed for SARS-CoV-2 detect different antibody subtypes and are based on different target antigens. Comparison of the performance of a SARS-CoV-2 Spike-Protein ELISA and the nucleocapsid-based Abbott ArchitectTM SARS-CoV-2 IgG assay indicated that the assays had high concordance, with rare paired discordant tests results.
- Subjects
SARS-CoV-2; IMMUNOGLOBULIN G; PROTEINS; ARCHITECTS; ANTIGENS
- Publication
PLoS ONE, 2021, Vol 16, Issue 7, p1
- ISSN
1932-6203
- Publication type
Article
- DOI
10.1371/journal.pone.0255208