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- Title
The Effect of Chronic Swimming Exercise and Vitamin E Supplementation on Bone Element Metabolism in Epileptic Rats.
- Authors
BALTACI, Saltuk Buğra; TUTKUN, Erkut; AYYILDIZ, Mustafa; AĞAR, Erdal; ARSLAN, Gökhan; MOĞULKOÇ, Rasim; BALTACI, Abdülkerim Kasım
- Abstract
Introduction: This study aimed to investigate the effects of chronic swimming exercise and vitamin E administration on elemental levels in the bone tissue of epileptic rats. Methods: Forty-eight rats were divided into six groups: Control, Swimming, Swimming + vitamin E, Swimming + Epilepsy, Swimming + Epilepsy + vitamin E, and Epilepsy. Vitamin E was administered to the animals chronically by gavage at a dose of 500 mg/kg every other day for 3 months. Epileptiform activity was induced with penicillin in animals 24 hours after the last vitamin E intake. The exercise program consisted of daily 30-minute swimming sessions. At the end of the treatment period, the levels of calcium, chromium, copper, iron, magnesium, manganese, lead, and zinc (µg/gram tissue) in bone tissue samples were measured using an atomic emission device. Results: The results showed that all epileptic groups had significantly lower bone chromium levels compared to the control groups (p<0.05). The epileptic, and epileptic swimming groups had the lowest levels of bone calcium, magnesium, and zinc (p<0.05). Vitamin E administration resulted in a significant increase in bone calcium, magnesium, and zinc levels in the epileptic swimming group with vitamin E compared to the epileptic and epileptic swimming groups. (p<0.05). Conclusion: The findings of the study show that the administration of vitamin E improves calcium, magnesium, and zinc metabolism in the deteriorated bone tissue of the epileptic rat model.
- Subjects
ZINC analysis; COPPER analysis; ANALYSIS of bones; IRON analysis; LEAD analysis; CHROMIUM analysis; TREATMENT of epilepsy; EXERCISE physiology; IRON in the body; MANGANESE; GASTRIC intubation; MAGNESIUM; CHEMICAL elements; EXERCISE therapy; DESCRIPTIVE statistics; RATS; CALCIUM; SWIMMING; VITAMIN E; ANIMAL experimentation; PENICILLIN
- Publication
Archives of Neuropsychiatry / Nöropsikiyatri Arşivi, 2024, Vol 61, Issue 2, p113
- ISSN
1300-0667
- Publication type
Article
- DOI
10.29399/npa.28495