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- Title
Two Cases of Subcutaneous Tuberculous Granuloma Associated with BCG Vaccination.
- Authors
KIGAWA, Tadayuki; KAWAI, Mayu; YAMAOKA, Hanako; KONDOH, Akio; TOJO, Masahiro; MABUCHI, Tomotaka
- Abstract
In recent years, BCG vaccination is routinely performed worldwide. The Ministry of Health, Labor and Welfare of Japan reported that the vaccination rate was as high as 92.9% in 2011. Majority of the reported local adverse reactions to BCG vaccination included lymph node swelling, keloid formation, and abscesses. Subcutaneous tuberculous granuloma is a rare local adverse reaction to BCG vaccination. Herein, we report two cases of developing subcutaneous tuberculous granuloma associated with BCG vaccination. Both of them were treated with isoniazid. There is no standard management for BCG-induced subcutaneous tuberculous granuloma, however, treatment with anti-tuberculosis drugs should be considered for cases of BCGinduced subcutaneous tuberculous granuloma with abscesses or ulcerations.
- Subjects
GRANULOMA; BCG vaccines; VACCINATION complications; DRUG side effects; ISONIAZID; ANTITUBERCULAR agents
- Publication
Tokai Journal of Experimental & Clinical Medicine, 2020, Vol 45, Issue 3, p136
- ISSN
0385-0005
- Publication type
Case Study