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- Title
CT enterography in obscure gastrointestinal bleeding: A systematic review and meta-analysis.
- Authors
Wang, Zhen; Chen, Jun‐qiang; Liu, Jin‐lu; Qin, Xin‐gan; Huang, Yuan
- Abstract
The objective of this article is to provide a comprehensive and update overview of clinical application of CT enterography ( CTE) in the evaluation of obscure gastrointestinal bleeding ( OGIB). We performed a systematic review of relevant literatures in Pub Med, EMBASE and The Cochrane Library and pooled the yield of CTE and the incremental yield ( IY) of CTE over an alternate modality. A total of 18 studies ( n = 660) reported the yield of CTE in evaluating OGIB and the pooled yield was 40% (95% confidence interval ( CI): 33-49%). Seven studies ( n = 279) compared the yield of CTE with capsule endoscopy ( CE). The yield for CTE and CE for all findings was 34% and 53%, respectively ( IY = −19%, 95% CI = −34% to −4%). When considering the types of identified lesions, the yield was significantly different for vascular and inflammatory lesions but not significantly different for neoplastic or other lesions. Two studies ( n = 63) compared the yield of CTE with double-balloon enteroscopy ( DBE). The yield for CTE and DBE was 38% and 78%, respectively ( IY = −40%, 95% CI = −55% to −25%). Three studies ( n = 49) compared the yield of CTE with digital subtraction angiography. The yield for CTE and digital subtraction angiography was 64% and 60%, respectively ( IY = 4%, 95% CI = −40% to 47%). CTE is an excellent diagnostic tool in patients with OGIB. It may play a complementary role to CE and can be used as a triage tool prior to DBE in evaluating OGIB.
- Subjects
GASTROINTESTINAL disease diagnosis; RADIOSCOPIC diagnosis; DIGITAL angiography; META-analysis; ENTEROSCOPY; INTESTINE examination
- Publication
Journal of Medical Imaging & Radiation Oncology, 2013, Vol 57, Issue 3, p263
- ISSN
1754-9477
- Publication type
Article
- DOI
10.1111/1754-9485.12035