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Deletion of the Brain-Specific α and δ Isoforms of Adapter Protein SH2B1 Protects Mice From Obesity.
Published in:
2021
By:
- Cote, Jessica L.;
- Argetsinger, Lawrence S.;
- Flores, Anabel;
- Rupp, Alan C.;
- Cline, Joel M.;
- DeSantis, Lauren C.;
- Bedard, Alexander H.;
- Bagchi, Devika P.;
- Vander, Paul B.;
- Cacciaglia, Abrielle M.;
- Clutter, Erik S.;
- Chandrashekar, Gowri;
- MacDougald, Ormond A.;
- Myers Jr., Martin G.;
- Carter-Su, Christin;
- Myers, Martin G Jr
Publication type:
journal article
Takes New Steps to Increase Transparency and Reproducibility.
Published in:
2019
By:
- Myers Jr., Martin G.;
- Myers, Martin G Jr.,;
- Diabetes Editorial Team
Publication type:
editorial
A Call for Improved Reporting of Human Islet Characteristics in Research Articles.
Published in:
2019
By:
- Poitout, Vincent;
- Satin, Leslie S.;
- Kahn, Steven E.;
- Stoffers, Doris A.;
- Marchetti, Piero;
- Gannon, Maureen;
- Verchere, C. Bruce;
- Herold, Kevan C.;
- Myers Jr., Martin G.;
- Marshall, Sally M.;
- Myers, Martin G Jr
Publication type:
editorial
Defining the Transcriptional Targets of Leptin Reveals a Role for in Leptin Action.
Published in:
2018
By:
- Allison, Margaret B.;
- Pan, Warren;
- MacKenzie, Alexander;
- Patterson, Christa;
- Shah, Kimi;
- Barnes, Tammy;
- Wenwen Cheng;
- Rupp, Alan;
- Olson, David P.;
- Myers Jr., Martin G.;
- Cheng, Wenwen;
- Myers, Martin G Jr
Publication type:
journal article
A Few Words of Introduction From Your New Diabetes Editorial Board.
Published in:
2017
By:
- Myers Jr., Martin G.;
- Myers, Martin G Jr
Publication type:
editorial
The Brain-to-Pancreatic Islet Neuronal Map Reveals Differential Glucose Regulation From Distinct Hypothalamic Regions.
Published in:
2016
By:
- Rosario, Wilfredo;
- Singh, Inderroop;
- Wautlet, Arnaud;
- Patterson, Christa;
- Flak, Jonathan;
- Becker, Thomas C.;
- Ali, Almas;
- Tamarina, Natalia;
- Philipson, Louis H.;
- Enquist, Lynn W.;
- Myers Jr., Martin G.;
- Rhodes, Christopher J.;
- Myers, Martin G Jr
Publication type:
journal article
Euglycemia Restoration by Central Leptin in Type 1 Diabetes Requires STAT3 Signaling but Not Fast-Acting Neurotransmitter Release.
Published in:
2016
By:
- Yuanzhong Xu;
- Chang, Jeffrey T.;
- Myers Jr., Martin G.;
- Yong Xu;
- Qingchun Tong;
- Xu, Yuanzhong;
- Myers, Martin G Jr;
- Xu, Yong;
- Tong, Qingchun
Publication type:
journal article
LRb-STAT3 signaling is required for the neuroendocrine regulation of energy expenditure by leptin.
Published in:
2004
By:
- Bates, Sarah H.;
- Dundon, Trevor A.;
- Seifert, Matthew;
- Carlson, Michael;
- Maratos-Flier, Eleftheria;
- Myers Jr., Martin G.;
- Myers, Martin G Jr
Publication type:
journal article
Insulin activation of phosphatidylinositol 3-kinase in the hypothalamic arcuate nucleus: a key mediator of insulin-induced anorexia.
Published in:
2003
By:
- Niswender, Kevin D.;
- Morrison, Christopher D.;
- Clegg, Deborah J.;
- Olson, Ryan;
- Baskin, Denis G.;
- Myers Jr., Martin G.;
- Seeley, Randy J.;
- Schwartz, Michael W.;
- Myers, Martin G Jr
Publication type:
journal article
Hypothalamic ER-associated degradation regulates POMC maturation, feeding, and age-associated obesity.
Published in:
2018
By:
- Geun Hyang Kim;
- Guojun Shi;
- Somlo, Diane R. M.;
- Haataja, Leena;
- Soobin Song;
- Qiaoming Long;
- Nillni, Eduardo A.;
- Low, Malcolm J.;
- Arvan, Peter;
- Myers Jr., Martin G.;
- Ling Qi;
- Kim, Geun Hyang;
- Shi, Guojun;
- Somlo, Diane Rm;
- Song, Soobin;
- Long, Qiaoming;
- Myers, Martin G Jr.;
- Qi, Ling
Publication type:
journal article
A leptin-regulated circuit controls glucose mobilization during noxious stimuli.
Published in:
2017
By:
- Flak, Jonathan N.;
- Arble, Deanna;
- Pan, Warren;
- Patterson, Christa;
- Lanigan, Thomas;
- Goforth, Paulette B.;
- Sacksner, Jamie;
- Joosten, Maja;
- Morgan, Donald A.;
- Allison, Margaret B.;
- Hayes, John;
- Feldman, Eva;
- Seeley, Randy J.;
- Olson, David P.;
- Rahmouni, Kamal;
- Myers Jr., Martin G.;
- Myers, Martin G Jr
Publication type:
journal article
Mice lacking inhibitory leptin receptor signals are lean with normal endocrine function.
Published in:
2007
By:
- Björnholm, Marie;
- Münzberg, Heike;
- Leshan, Rebecca L.;
- Villanueva, Eneida C.;
- Bates, Sarah H.;
- Louis, Gwendolyn W.;
- Jones, Justin C.;
- Ishida-Takahashi, Ryoko;
- Bjørbaek, Christian;
- Myers Jr., Martin G.;
- Björnholm, Marie;
- Münzberg, Heike;
- Bjørbaek, Christian;
- Myers, Martin G Jr
Publication type:
journal article
An Osteoblast-dependent Mechanism Contributes to the Leptin Regulation of Insulin Secretion.
Published in:
Annals of the New York Academy of Sciences, 2009, v. 1173, p. E20, doi. 10.1111/j.1749-6632.2009.05061.x
By:
- Hinoi, Eiichi;
- Gao, Nan;
- Jung, Dae Young;
- Yadav, Vijay;
- Yoshizawa, Tatsuya;
- Kajimura, Daisuke;
- Myers, Jr., Martin G.;
- Chua, Jr., Streamson C.;
- Wang, Qin;
- Kim, Jason K.;
- Kaestner, Klaus H.;
- Karsenty, Gerard
Publication type:
Article
Taste Responsiveness to Sweeteners Is Resistant to Elevations in Plasma Leptin.
Published in:
Chemical Senses, 2015, v. 40, n. 4, p. 223, doi. 10.1093/chemse/bju075
By:
- Glendinning, John I.;
- Elson, Amanda E. T.;
- Kalik, Salina;
- Sosa, Yvett;
- Patterson, Christa M.;
- Myers Jr, Martin G.;
- Munger, Steven D.
Publication type:
Article
Direct Innervation of GnRH Neurons by Metabolic- and Sexual Odorant-Sensing Leptin Receptor Neurons in the Hypothalamic Ventral Premammillary Nucleus.
Published in:
Journal of Neuroscience, 2009, v. 29, n. 10, p. 3138, doi. 10.1523/JNEUROSCI.0155-09.2009
By:
- Leshan, Rebecca L.;
- Louis, Gwendolyn W.;
- Young-Hwan Jo;
- Rhodes, Christopher J.;
- Münzberg, Heike;
- Myers Jr, Martin G.
Publication type:
Article
Appropriate Inhibition of Orexigenic Hypothalamic Arcuate Nucleus Neurons Independently of Leptin Receptor/STAT3 Signaling.
Published in:
Journal of Neuroscience, 2007, v. 27, n. 1, p. 69, doi. 10.1523/JNEUROSCI.3168-06.2007
By:
- Münzberg, Heike;
- Jobst, Erin E.;
- Bates, Sarah H.;
- Jones, Justin;
- Villanueva, Eneida;
- Leshan, Rebecca;
- Björnholm, Marie;
- Elmquist, Joel;
- Sleeman, Mark;
- Cowley, Michael A.;
- Myers Jr., Martin G.
Publication type:
Article
Role of the Beta and Gamma Isoforms of the Adapter Protein SH2B1 in Regulating Energy Balance.
Published in:
Endocrinology, 2023, v. 164, n. 5, p. 1, doi. 10.1210/endocr/bqad032
By:
- Argetsinger, Lawrence S;
- Flores, Anabel;
- Svezhova, Nadezhda;
- Ellis, Michael;
- Reynolds, Caitlin;
- Cote, Jessica L;
- Cline, Joel M;
- Myers Jr, Martin G;
- Carter-Su, Christin
Publication type:
Article
Lateral Hypothalamic Mc3R-Expressing Neurons Modulate Locomotor Activity, Energy Expenditure, and Adiposity in Male Mice.
Published in:
Endocrinology, 2019, v. 160, n. 2, p. 343, doi. 10.1210/en.2018-00747
By:
- Hongjuan Pei;
- Patterson, Christa M.;
- Sutton, Amy K.;
- Burnett, Korri H.;
- Myers Jr, Martin G.;
- Olson, David P.
Publication type:
Article
The New Elements of Insulin Signaling.
Published in:
Diabetes, 1993, v. 42, n. 5, p. 643, doi. 10.2337/diab.42.5.643
By:
- Myers Jr., Martin G.;
- White, Morris J.
Publication type:
Article
Functional Consequences of the Human Leptin Receptor (LEPR) Q223R Transversion.
Published in:
Obesity (19307381), 2009, v. 17, n. 1, p. 126, doi. 10.1038/oby.2008.489
By:
- Stratigopoulos, George;
- LeDuc, Charles A.;
- Matsuoka, Naoki;
- Gutman, Roee;
- Rausch, Richard;
- Robertson, Scott A.;
- Myers Jr., Martin G.;
- Chung, Wendy K.;
- Chua Jr., Streamson C.;
- Leibel, Rudolph L.
Publication type:
Article
Leptin receptor signaling and action in the central nervous system.
Published in:
2006
By:
- Leshan, Rebecca L.;
- Björnholm, Marie;
- Münzberg, Heike;
- Myers, Martin G.;
- Björnholm, Marie;
- Münzberg, Heike;
- Myers, Martin G Jr
Publication type:
journal article
Molecular and anatomical determinants of central leptin resistance.
Published in:
Nature Neuroscience, 2005, v. 8, n. 5, p. 566, doi. 10.1038/nn1454
By:
- Münzberg, Heike;
- Myers Jr., Martin G.
Publication type:
Article
How Leptin Controls the Drive to Eat.
Published in:
Korean Journal of Obesity (2383-899X), 2015, v. 24, n. 2, p. 69, doi. 10.7570/kjo.2015.24.2.69
By:
- Patterson, Christa M.;
- Myers, Jr., Martin G.
Publication type:
Article
The sympathetic tone mediates leptin's inhibition of insulin secretion by modulating osteocalcin bioactivity.
Published in:
Journal of Cell Biology, 2008, v. 183, n. 7, p. 1235, doi. 10.1083/jcb.200809113
By:
- Hinoi, Eiichi;
- Gao, Nan;
- Jung, Dae Young;
- Yadav, Vijay;
- Yoshizawa, Tatsuya;
- Myers Jr., Martin G.;
- Chua Jr., Streamson C.;
- Kim, Jason K.;
- Kaestner, Klaus H.;
- Karsenty, Gerard
Publication type:
Article
NTS Prlh overcomes orexigenic stimuli and ameliorates dietary and genetic forms of obesity.
Published in:
Nature Communications, 2021, v. 12, n. 1, p. 1, doi. 10.1038/s41467-021-25525-3
By:
- Cheng, Wenwen;
- Ndoka, Ermelinda;
- Maung, Jessica N.;
- Pan, Warren;
- Rupp, Alan C.;
- Rhodes, Christopher J.;
- Olson, David P.;
- Myers Jr, Martin G.
Publication type:
Article
Integration of stress and leptin signaling by CART producing neurons in the rodent midbrain centrally projecting Edinger-Westphal nucleus.
Published in:
Frontiers in Neuroanatomy, 2014, v. 8, p. 1, doi. 10.3389/fnana.2014.00008
By:
- Lu Xu;
- Janssen, Donny;
- van der Knaap, Noortje;
- Roubos, Eric W.;
- Leshan, Rebecca L.;
- Myers Jr, Martin G.;
- Gaszner, Balázs;
- Kozicz, Tamás
Publication type:
Article
TBK1-mTOR Signaling Attenuates Obesity-Linked Hyperglycemia and Insulin Resistance.
Published in:
Diabetes, 2022, v. 71, n. 11, p. 2297, doi. 10.2337/db22-0256
By:
- Bodur, Cagri;
- Kazyken, Dubek;
- Huang, Kezhen;
- Tooley, Aaron Seth;
- Cho, Kae Won;
- Barnes, Tammy M.;
- Lumeng, Carey N.;
- Myers Jr., Martin G.;
- Fingar, Diane C.
Publication type:
Article
1778-P: A Single Cell Map of Metabolically Regulated Neurons in the Ventromedial Hypothalamic Nucleus.
Published in:
Diabetes, 2020, v. 69, p. N.PAG, doi. 10.2337/db20-1778-P
By:
- RUPP, ALAN;
- AFFINATI, ALISON;
- MYERS JR., MARTIN G.
Publication type:
Article
1760-P: Brain Sh2b1 Protects against Obesity and Insulin Resistance through Multiple Hypothalamic Neural Circuits.
Published in:
Diabetes, 2020, v. 69, p. N.PAG, doi. 10.2337/db20-1760-P
By:
- LI, YUAN;
- KIM, MIN-HYUN;
- JIANG, LIN;
- MYERS JR., MARTIN G.;
- RUI, LIANGYOU
Publication type:
Article
215-OR: Silencing CCKBR Containing Neurons in the VMN Restrains Hepatic Glucose Production to Ameliorate Diabetes in Mice.
Published in:
Diabetes, 2020, v. 69, p. N.PAG, doi. 10.2337/db20-215-OR
By:
- AFFINATI, ALISON;
- FLAK, JONATHAN;
- BOZADJIEVA, NADEJDA;
- KODUR, NANDAN;
- CRAS-MÉNEUR, CORENTIN M.;
- SANDOVAL, DARLEEN A.;
- MYERS JR., MARTIN G.
Publication type:
Article
211-OR: Hypothalamic Slug Couples Overnutrition States to Epigenetic Reprogramming of Leptin Neural Circuits, Obesity, and Type 2 Diabetes.
Published in:
Diabetes, 2020, v. 69, p. N.PAG, doi. 10.2337/db20-211-OR
By:
- KIM, MIN-HYUN;
- JIANG, LIN;
- MYERS JR., MARTIN G.;
- RUI, LIANGYOU
Publication type:
Article
196-LB: Synergetic and Distinct Roles in the Control of Food Intake and Energy Balance for Subpopulations of NTS Neurons.
Published in:
Diabetes, 2020, v. 69, p. N.PAG, doi. 10.2337/db20-196-LB
By:
- CHENG, WENWEN C.;
- NDOKA, ERMELINDA;
- MAERZ, BASMA;
- ROELOFS, KAREN J.;
- RHODES, CHRISTOPHER J.;
- SEELEY, RANDY J.;
- SANDOVAL, DARLEEN A.;
- OLSON, DAVID;
- MYERS JR., MARTIN G.
Publication type:
Article
Crucial Role of the SH2B1 PH Domain for the Control of Energy Balance.
Published in:
2019
By:
- Flores, Anabel;
- Argetsinger, Lawrence S.;
- Stadler, Lukas K. J.;
- Malaga, Alvaro E.;
- Vander, Paul B.;
- DeSantis, Lauren C.;
- Joe, Ray M.;
- Cline, Joel M.;
- Keogh, Julia M.;
- Henning, Elana;
- Barroso, Ines;
- Mendes de Oliveira, Edson;
- Chandrashekar, Gowri;
- Clutter, Erik S.;
- Yixin Hu;
- Stuckey, Jeanne;
- Farooqi, I. Sadaf;
- Myers Jr., Martin G.;
- Carter-Su, Christin;
- Hu, Yixin
Publication type:
journal article
A Special Thanks to the Reviewers of .
Published in:
2017
By:
- Myers Jr., Martin G.
Publication type:
editorial
Ectopic Expression of Col2.3 and Col3.6 Promoters in the Brain and Association with Leptin Signaling.
Published in:
Cells Tissues Organs, 2011, v. 194, n. 2-4, p. 268, doi. 10.1159/000324745
By:
- Scheller, Erica L.;
- Leinninger, Gina M.;
- Hankenson, Kurt D.;
- Myers, Jr., Martin G.;
- Krebsbach, Paul H.
Publication type:
Article
The Islet Estrogen Receptor-α Is Induced by Hyperglycemia and Protects Against Oxidative Stress-Induced Insulin-Deficient Diabetes.
Published in:
PLoS ONE, 2014, v. 9, n. 2, p. 1, doi. 10.1371/journal.pone.0087941
By:
- Kilic, Gamze;
- Alvarez-Mercado, Ana I.;
- Zarrouki, Bader;
- Opland, Darren;
- Liew, Chong Wee;
- Alonso, Laura C.;
- Myers Jr, Martin G.;
- Jonas, Jean-Christophe;
- Poitout, Vincent;
- Kulkarni, Rohit N.;
- Mauvais-Jarvis, Franck
Publication type:
Article
Loss of Cytokine-STAT5 Signaling in the CNS and Pituitary Gland Alters Energy Balance and Leads to Obesity.
Published in:
PLoS ONE, 2008, v. 3, n. 2, p. 1, doi. 10.1371/journal.pone.0001639
By:
- Ji-Yeon Lee;
- Muenzberg, Heike;
- Gavrilova, Oksana;
- Reed, Jacquelyn A.;
- Berryman, Darlene;
- Villanueva, Eneida C.;
- Louis, Gwendolyn W.;
- Leinninger, Gina M.;
- Bertuzzi, Stefano;
- Seeley, Randy J.;
- Robinson, Gertraud W.;
- Myers Jr., Martin G.;
- Hennighausen, Lothar
Publication type:
Article
Keeping the fat off with nesfatin.
Published in:
Nature Medicine, 2006, v. 12, n. 11, p. 1248, doi. 10.1038/nm1106-1248
By:
- Myers, Jr., Martin G.
Publication type:
Article
Control of Food Intake and Energy Expenditure by Nosl Neurons of the Paraventricular Hypothalamus.
Published in:
Journal of Neuroscience, 2014, v. 34, n. 46, p. 15306, doi. 10.1523/JNEUROSCI.0226-14.2014
By:
- Sutton, Amy K.;
- Pei, Hongjuan;
- Burnett, Korri H.;
- Myers Jr., Martin G.;
- Rhodes, Christopher J.;
- Olson, David P.
Publication type:
Article
Leptin Acts via Lateral Hypothalamic Area Neurotensin Neurons to Inhibit Orexin Neurons by Multiple GABA-Independent Mechanisms.
Published in:
Journal of Neuroscience, 2014, v. 34, n. 34, p. 11405, doi. 10.1523/JNEUROSCI.5167-13.2014
By:
- Goforth, Paulette B.;
- Leinninger, Gina M.;
- Patterson, Christa M.;
- Satin, Leslie S.;
- Myers Jr, Martin G.
Publication type:
Article
Distinct Roles for Specific Leptin Receptor Signals in the Development of Hypothalamic Feeding Circuits.
Published in:
Journal of Neuroscience, 2012, v. 32, n. 4, p. 1244, doi. 10.1523/JNEUROSCI.2277-11.2012
By:
- Bouret, Sebastien G.;
- Bates, Sarah H.;
- Chen, Stephen;
- Myers Jr, Martin G.;
- Simerly, Richard B.
Publication type:
Article
Inflammation-Induced Lethargy Is Mediated by Suppression of Orexin Neuron Activity.
Published in:
Journal of Neuroscience, 2011, v. 31, n. 31, p. 11376, doi. 10.1523/JNEUROSCI.2311-11.2011
By:
- Grossberg, Aaron J.;
- XinXia Zhu;
- Leinninger, Gina M.;
- Levasseur, Peter R.;
- Braun, Theodore P.;
- Myers Jr., Martin G.;
- Marks, Daniel L.
Publication type:
Article
Direct Innervation and Modulation of Orexin Neurons by Lateral Hypothalamic LepRb Neurons.
Published in:
Journal of Neuroscience, 2010, v. 30, n. 34, p. 11278, doi. 10.1523/JNEUROSCI.1340-10.2010
By:
- Louis, Gwendolyn W.;
- Leinninger, Gina M.;
- Rhodes, Christopher J.;
- Myers Jr., Martin G.
Publication type:
Article
Ventral Tegmental Area Leptin Receptor Neurons Specifically Project to and Regulate Cocaine- and Amphetamine-Regulated Transcript Neurons of the Extended Central Amygdala.
Published in:
Journal of Neuroscience, 2010, v. 30, n. 16, p. 5713, doi. 10.1523/JNEUROSCI.1001-10.2010
By:
- Leshan, Rebecca L.;
- Opland, Darren M.;
- Louis, Gwendolyn W.;
- Leinninger, Gina M.;
- Patterson, Christa M.;
- Rhodes, Christopher J.;
- Münzberg, Heike;
- Myers Jr, Martin G.
Publication type:
Article
Neuropeptide Y Suppresses Anorexigenic Output from the Ventromedial Nucleus of the Hypothalamus.
Published in:
Journal of Neuroscience, 2010, v. 30, n. 9, p. 3380, doi. 10.1523/JNEUROSCI.4031-09.2010
By:
- Chee, Melissa J. S.;
- Myers Jr, Martin G.;
- Price, Christopher J.;
- Colmers, William F.
Publication type:
Article
Key enzyme in leptin-induced anorexia.
Published in:
Nature, 2001, v. 413, n. 6858, p. 794, doi. 10.1038/35101657
By:
- Niswender, Kevin D.;
- Morton, Gregory J.;
- Stearns, Walter H.;
- Rhodes, Christopher J.;
- Myers Jr., Martin G.;
- Schwartz, Michael W.
Publication type:
Article
Glutamatergic Transmission to Hypothalamic Kisspeptin Neurons Is Differentially Regulated by Estradiol through Estrogen Receptor αin Adult Female Mice.
Published in:
Journal of Neuroscience, 2018, v. 38, n. 5, p. 1061, doi. 10.1523/JNEUROSCI.2428-17.2017
By:
- Luhong Wang;
- Burger, Laura L.;
- Greenwald-Yarnell, Megan L.;
- Myers Jr., Martin G.;
- Moenter, Suzanne M.
Publication type:
Article
Conditional Gene Targeting in Mouse Pancreatic β-Cells.
Published in:
Diabetes, 2010, v. 59, n. 12, p. 3090, doi. 10.2337/db10-0624
By:
- Wicksteed, Barton;
- Brissova, Marcela;
- Yan, Wenbo;
- Opland, Darren M.;
- Plank, Jennifer L.;
- Reinert, Rachel B.;
- Dickson, Lorna M.;
- Tamarina, Natalia A.;
- Philipson, Louis H.;
- Shostak, Alena;
- Bernal-Mizrachi, Ernesto;
- Elghazi, Lynda;
- Roe, Michael W.;
- Labosky, Patricia A.;
- Myers Jr., Martin G.;
- Gannon, Maureen;
- Powers, Alvin C.;
- Dempsey, Peter J.
Publication type:
Article
Outstanding Scientific Achievement Award Lecture 2010: Deconstructing Leptin: From Signals to Circuits.
Published in:
Diabetes, 2010, v. 59, n. 11, p. 2708, doi. 10.2337/db10-1118
By:
- Myers Jr., Martin G.
Publication type:
Article
Insufficiency of Janus kinase 2-autonomous leptin receptor signals for most physiologic leptin actions.
Published in:
2010
By:
- Robertson S;
- Ishida-Takahashi R;
- Tawara I;
- Hu J;
- Patterson CM;
- Jones JC;
- Kulkarni RN;
- Myers MG Jr;
- Robertson, Scott;
- Ishida-Takahashi, Ryoko;
- Tawara, Isao;
- Hu, Jiang;
- Patterson, Christa M;
- Jones, Justin C;
- Kulkarni, Rohit N;
- Myers, Martin G Jr
Publication type:
journal article

Found: 59