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- Title
Isoflurane Hepatotoxicity: A Case Report and Review of the Literature.
- Authors
Sinha, Alok; Clatch, Richard John; Stuck, Gary; Blumenthal, Stanley A.; Patel, Samir A.
- Abstract
Isoflurane, hailed as the anesthetic of the 1980s, is less hepatutoxic than its predecessors, halothane and enflurane. Since its release by the Food and Drug Administration in 1979, controversy has existed about the extent to which isoflurane is capable of producing hepatotoxic effects. In this report, we provide direct evidence that isoflurane can induce liver injury and should therefore be considered as a potential cause of serum transaminase elevations in any patient who is exposed to this anesthetic.
- Subjects
ISOFLURANE; ANESTHETICS; HEPATOTOXICOLOGY; LIVER diseases; HALOTHANE; ENFLURANE
- Publication
American Journal of Gastroenterology (Springer Nature), 1996, Vol 91, Issue 11, p2406
- ISSN
0002-9270
- Publication type
Article