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- Title
Pharmaco-vigilance of oral MethylErgometrine prescriptions for delayed and secondary postpartum haemorrhage.
- Authors
Pallivalapila, Abdul Rouf; Babarinsa, Isaac A.; Al-Baloushi, Mariam; Moursi, Ahmed; Bayo, Arabo; Thomas, Binny; Mahmoud Mohd, Mahmoud G
- Abstract
Objectives: The objectives of this study were to quantify the prescription of oral methergin tablets in a busy Women's Hospital, assess the stated indications for such prescription and highlight the issues and safety profile of Methergin use especially in the postpartum patient. Methods: Review of prescription data for oral Methergin and the corresponding annual figures on primary and secondary postpartum hemorrhage. Results: Over a period of 5 years, oral Methergin prescriptions for delayed and secondary postpartum hemorrhage constituted less than 1% of the overall prescription in Obstetrics and Gynaecology, which ranged between 1214 and 2085 per year. The numbers were too few to ascertain any relationship with both types of postpartum hemorrhage. Although stated on the relevant Patient Information leaflet, no local or regional guideline on its use exist. Conclusions: Specific and random trend monitoring of medications for continuing safety profile, risk benefit issues, or unapproved indication, may help in identifying, preventing and mitigating any medication safety matters. Clinical pharmacists in collaboration with physicians are well placed in conducting such pharmacovigilance activities to improve medication safety.
- Subjects
DRUG prescribing; HEMORRHAGE; HOSPITALS; MEDICAL prescriptions; ORAL drug administration; PATIENT safety; PHARMACOLOGY; PHYSICIANS; PUERPERAL disorders; DRUG tablets; WOMEN'S health services; PHYSICIAN practice patterns; QUANTITATIVE research; ERGOMETRINE
- Publication
Journal of Perinatal Medicine, 2020, Vol 48, Issue 8, p853
- ISSN
0300-5577
- Publication type
Article
- DOI
10.1515/jpm-2020-0128