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- Title
Crohn's disease is associated with higher rates of implant-related complications following primary total knee arthroplasty.
- Authors
Pandya, Radha P.; Ganesan, Vanathi; Rodriguez, Ariel N.; Magruder, Matthew L.; Wong, Che Hang Jason; Choueka, Jack; Razi, Afshin E.
- Abstract
Introduction: In Western countries, there has been a rise in the prevalence of Crohn's Disease (CD) and primary total knee arthroplasty (TKA). This study delves deeper into the effects of CD on TKA patients by examining (1) the length of in-hospital stay (LOS); (2) the rates of readmission; (3) complications related to implants; and (4) the costs associated with care. Methods: A retrospective analysis using the PearlDiver database was conducted, encompassing the time frame between January 1st, 2005 and March 31st, 2014, focusing on patients who underwent TKA and were either diagnosed with CD or not. Patients with CD were paired with control subjects at a 1:5 ratio based on age, gender, and medical comorbidities. The analysis comprised a total of 96,229 patients (CD = 16,039; non-CD = 80,190). Results: Patients with CD had a notably longer hospital stay (3 v. 2 days, p < 0.0001) and faced significantly higher rates of 90-day readmissions and complications (19.80% v. 14.91%, OR: 1.40, p < 0.0001; 6.88% v. 4.88%, OR: 1.43, p < 0.0001 respectively). Additionally, CD patients incurred greater expenses on the surgery day ($18,365.98 v. $16,192.00) and within 90 days post-surgery ($21,337.46 v. $19,101.42). Conclusion: This study demonstrates longer in-hospital LOS, higher rates of readmissions, implant-related complications, and costs of care among CD patients following primary TKA.
- Subjects
RISK assessment; PROSTHETICS; PEARSON correlation (Statistics); CROHN'S disease; PROSTHESIS-related infections; T-test (Statistics); DATA analysis; PATIENT readmissions; SEX distribution; LOGISTIC regression analysis; ARTIFICIAL implants; RETROSPECTIVE studies; AGE distribution; CHI-squared test; DESCRIPTIVE statistics; SURGICAL complications; ODDS ratio; TOTAL knee replacement; MEDICAL records; ACQUISITION of data; STATISTICS; LENGTH of stay in hospitals; CONFIDENCE intervals; MEDICAL care costs; TIME; COMORBIDITY; DISEASE risk factors
- Publication
European Journal of Orthopaedic Surgery & Traumatology, 2024, Vol 34, Issue 3, p1357
- ISSN
1633-8065
- Publication type
Article
- DOI
10.1007/s00590-023-03794-6