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- Title
Tailored RF pulse for magnetization inversion at ultrahigh field.
- Authors
Hurley, Aaron C.; Al-Radaideh, Ali; Bai, Li; Aickelin, Uwe; Coxon, Ron; Glover, Paul; Gowland, Penny A.
- Abstract
The radiofrequency (RF) transmit field is severely inhomogeneous at ultrahigh field due to both RF penetration and RF coil design issues. This particularly impairs image quality for sequences that use inversion pulses such as magnetization prepared rapid acquisition gradient echo and limits the use of quantitative arterial spin labeling sequences such as flow-attenuated inversion recovery. Here we have used a search algorithm to produce inversion pulses tailored to take into account the heterogeneity of the RF transmit field at 7 T. This created a slice selective inversion pulse that worked well (good slice profile and uniform inversion) over the range of RF amplitudes typically obtained in the head at 7 T while still maintaining an experimentally achievable pulse length and pulse amplitude in the brain at 7 T. The pulses used were based on the frequency offset correction inversion technique, as well as time dilation of functions, but the RF amplitude, frequency sweep, and gradient functions were all generated using a genetic algorithm with an evaluation function that took into account both the desired inversion profile and the transmit field inhomogeneity. Magn Reson Med, 2009. © 2009 Wiley-Liss, Inc.
- Publication
Magnetic Resonance in Medicine, 2010, Vol 63, Issue 1, p51
- ISSN
0740-3194
- Publication type
Article
- DOI
10.1002/mrm.22167