We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Oncologic outcome of colorectal cancer patients over age 80: a propensity score-matched analysis.
- Authors
Oh, Bo Young; Huh, Jung Wook; Kim, Hee Cheol; Park, Yoon Ah; Cho, Yong Beom; Yun, Seong Hyeon; Lee, Woo Yong; Chun, Ho-Kyung
- Abstract
Purpose: It remains unclear whether old age is a poor prognostic factor in colorectal cancer (CRC). We compared oncologic outcomes in CRC patients according to age, using 80 as the dividing point.Methods: CRC patients who underwent radical surgery from 2000 to 2011 were evaluated. We performed matched and adjusted analyses comparing oncologic outcomes between patients with ≥ 80 and < 80 years old.Results: Among 9562 patients, 222 were elderly. The median age was 82.0 years in elderly patients and 59.0 years in young patients. Elderly patients received less neoadjuvant or adjuvant therapy compared to young patients (p < 0.001). After recurrence, significantly fewer elderly patients received additional treatments (p < 0.001). Before matching, disease-free survival (DFS) and cancer-specific survival (CSS) were significantly lower for elderly patients compared to those for young patients (p < 0.001 and p < 0.001, respectively). After matching, DFS and CCS were not significantly different between the two groups (p = 0.400 and p = 0.267, respectively). In a multivariate analysis for prognostic factors, old age was not an independent poor prognostic factor of DFS and CCS (p = 0.619 and p = 0.137, respectively).Conclusions: Elderly patients aged ≥ 80 years with CRC had similar oncologic outcome to young patients, and age was not an independent prognostic factor.
- Subjects
COLON cancer patients; DISEASES in older people; CANCER invasiveness; CANCER radiotherapy; ADJUVANT treatment of cancer
- Publication
International Journal of Colorectal Disease, 2018, Vol 33, Issue 8, p1011
- ISSN
0179-1958
- Publication type
Article
- DOI
10.1007/s00384-018-3028-4