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- Title
An Assessment of In Ovo Toxicity of the Flame Retardant 1,2-Dibromo-4-(1,2-Dibromoethyl) Cyclohexane (TBECH) in the Zebra Finch.
- Authors
Currier, Heidi; Letcher, Robert; Williams, Tony; Elliott, John
- Abstract
Embryonic toxicity of a brominated flame retardant, TBECH (1,2-dibromo-4-(1, 2-dibromoethyl) cyclohexane) was investigated using the zebra finch ( Taeniopygia guttata) as our model. Using in ovo dosing procedures, we injected the technical TBECH compound, consisting of 50:50 α-/β-isomers, directly into the yolk of freshly laid eggs at concentrations of 2.3-94 ng/g egg. No significant effects were observed in terms of growth or survival for either pre-hatch embryos or post-hatch chicks. Analysis of tissue samples at various developmental stages suggests that α-/β-TBECH was metabolized rapidly, and thus is unlikely to cause any direct, long-term effects on the development of zebra finch embryos or offspring.
- Subjects
PHYSIOLOGICAL effects of fireproofing agents; TOXICOLOGY; CYCLOHEXANE; RISK assessment of water pollution; ZEBRA finch
- Publication
Bulletin of Environmental Contamination & Toxicology, 2013, Vol 91, Issue 4, p455
- ISSN
0007-4861
- Publication type
Article
- DOI
10.1007/s00128-013-1070-z