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- Title
Persistent Severe Acute Respiratory Syndrome Coronavirus 2 Pneumonia in Patients Treated With Anti-CD20 Monoclonal Antibodies.
- Authors
Furie, Nadav; Mandelboim, Michal; Zuckerman, Neta; Belkin, Ana; Seluk, Lior; Shafran, Inbal; Mass, Ronen; Levy, Liran; Chatterji, Sumit; Baltaxe, Erik; Peled, Michael; Shulimzon, Tiberiu; Avigdor, Abraham; Amit, Sharon; Onn, Amir; Marom, Edith M; Rahav, Galia; Segel, Michael J
- Abstract
We report 8 cases of persistent severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pneumonia in patients previously treated with anti-CD20 monoclonal antibodies. Polymerase chain reaction of nasopharyngeal swabs for SARS-CoV-2 was negative in most cases; viral cell cultures confirmed that viable SARS-Co-2 virus was present. Four patients were treated with anti-SARS-CoV-2 hyperimmune globulins with rapid resolution of disease.
- Subjects
SARS-CoV-2; MONOCLONAL antibodies; CORONAVIRUS diseases
- Publication
Open Forum Infectious Diseases, 2023, Vol 10, Issue 10, p1
- ISSN
2328-8957
- Publication type
Case Study
- DOI
10.1093/ofid/ofad464