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- Title
Intestinal mucormycosis initially identified by next‐generation sequencing of cell‐free DNA.
- Authors
Martin‐Blais, Rachel; Pathak, Saumya; Fitzwater, Sean; Dawson, David W.; Sisk, Anthony E.; Farmer, Douglas G.; Venick, Robert; Yeganeh, Nava
- Abstract
Mucormycosis is a rare fungal infection that typically affects severely immunocompromised individuals, often resulting in significant morbidity and mortality. Although early and aggressive intervention is necessary to prevent poor outcomes, diagnosis of this infection remains difficult. We report the first case, to our knowledge, of invasive gastrointestinal mucormycosis initially identified by next‐generation sequencing of cfDNA from the blood, and discuss the various benefits and challenges which come with new molecular diagnostic techniques.
- Subjects
CELL-free DNA; DNA sequencing; NUCLEOTIDE sequencing; INTESTINES; MYCOSES; MUCORMYCOSIS
- Publication
Transplant Infectious Disease, 2021, Vol 23, Issue 4, p1
- ISSN
1398-2273
- Publication type
Article
- DOI
10.1111/tid.13656