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- Title
Use of organs from donors with bloodstream infection, pneumonia, and influenza: Results of a survey of infectious diseases practitioners.
- Authors
Mehta, Sanjay R.; Logan, Cathy; Kotton, Camille N.; Kumar, Deepali; Aslam, Saima
- Abstract
Background Potential organ donors may be admitted with an infection to an intensive care unit, or contract a nosocomial infection during their stay, increasing the risk of potential transmission to the recipient. Because of a lack of practice guidelines and large-scale data on this topic, we undertook a survey to assess the willingness of transplant infectious diseases ( ID) physicians to accept such organs. Methods We performed a 10-question survey of ID providers from the American Society of Transplantation Infectious Disease Community of Practice to determine the scope of practice regarding acceptance of organs from donors with bloodstream infection, pneumonia, and influenza prior to organ procurement, as well as management of such infections following transplantation. Results Among 60 respondents to our survey, a majority indicated that organs would be accepted from donors bacteremic with streptococci (76%) or Enterobacteriaceae (73%) without evidence of drug resistance. Acceptance rates varied based on infecting organism, type of organ, and center size. Ten percent of respondents would accept an organ from a donor bacteremic with a carbapenem-resistant organism. Over 90% of respondents would accept an organ other than a lung from a donor with influenza on treatment, compared with 52% that would accept a lung in the same setting. Conclusions This study is the first to our knowledge to survey transplant ID providers regarding acceptance of organs based on specific infections in the donor. These decisions are often based on limited published data and experience. Better characterization of the outcomes from donors with specific types of infection could lead to liberalization of organ acceptance practices across centers.
- Subjects
NOSOCOMIAL infections; PNEUMONIA; ENTEROBACTERIACEAE diseases; ORGAN donors; INTENSIVE care units; TRANSPLANTATION of organs, tissues, etc.; PATIENTS; DISEASE risk factors; THERAPEUTICS
- Publication
Transplant Infectious Disease, 2017, Vol 19, Issue 1, pn/a
- ISSN
1398-2273
- Publication type
Article
- DOI
10.1111/tid.12645