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- Title
Postprandial anti-hyperglycemic effect of vitamin B6 (pyridoxine) administration in healthy individuals.
- Authors
Kim, Hyuk Hwa; Kang, Yu-Ri; Choi, Hwang-Yong; Lee, Jung-Yun; Oh, Jung-Bae; Kim, Justin S.; Kim, Young-Cheul; Lee, Ki Won; Kwon, Young-In
- Abstract
Postprandial blood glucose lowering effect of vitamin B6 (pyridoxine) was evaluated in healthy individuals with normal blood glucose levels. Blood glucose levels were measured every 30 min for 2 h after oral sugar administration with or without 50 mg of pyridoxine. Pyridoxine significantly lowered the postprandial blood glucose levels at 30 min (from 165.95 ± 17.19 to 138.36 ± 20.43, p < 0.01) and 60 min (from 131.40 ± 17.20 to 118.50 ± 15.95) after administration. In addition, the area under the concentration–time curve (AUCt) was reduced by about 8.3% (from 257.08 ± 22.38 to 235.71 ± 12.33, p < 0.05) and the maximum concentration of blood glucose (Cmax) was reduced by about 13.8% (from 165.95 ± 17.19 to 143.07 ± 11.34, p < 0.01) when compared with those of the control group. Our findings suggest that pyridoxine supplementation may be beneficial for controlling postprandial hyperglycemia.
- Publication
Food Science & Biotechnology, 2019, Vol 28, Issue 3, p907
- ISSN
1226-7708
- Publication type
Article
- DOI
10.1007/s10068-018-0534-7