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- Title
Research progress of TRIMs protein family in tumors.
- Authors
YUANYUAN HUANG; HONGMEI WU; RUYUAN LIU; SONG JIN; WEILAI XIANG; CHANG YANG; LI XU; XIAONIAN ZHU
- Abstract
The tripartite motif (TRIMs) protein family has E3 ubiquitin ligase activity among most of its members. They participate in multiple cellular processes and signaling pathways in living organisms, including cell cycle, growth, and metabolism, and mediate chromatin modification, transcriptional regulation, post-translational modification, and cellular autophagy. Previous studies have confirmed that the TRIMs protein family is involved in the development of various cancers and correlated with the prognosis of tumor patients. Here we summarize the biological roles of the TRIMs protein family in cancers.
- Subjects
TRIM proteins; TUMORS; CELLULAR signal transduction; UBIQUITIN ligases; CELL cycle
- Publication
Biocell, 2023, Vol 47, Issue 3, p445
- ISSN
0327-9545
- Publication type
Article
- DOI
10.32604/biocell.2023.025880