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- Title
Individualized Glycemic Control in Type 2 Diabetic Patients in Iran: A Multi-Center Data Analysis.
- Authors
Sadeghi, Abolfazl; Bayazidi, Yahya; Davari, Majid; Kebriaeezadeh, Abbas; Assarian, Amin; Esteghamati, Alireza; Yousefi, Sepideh
- Abstract
Background: Clinical guidelines and expert committees have recently suggested that the hemoglobin A1C (HbA1c) should be individualized based on various criteria. Data regarding the achievement of individualized glycemic targets in type 2 diabetes mellitus (T2DM) patients is scant in Iran. We intended to provide information found on real-world outcomes from the perspective of an individualized recommendation. Methods: A cross-sectional analysis was conducted in 15 diabetes centers in Iran between 2013-2017. Two steps cluster sampling selection was used to recruit 1591 patients with T2DM. Considering Ismail-Beigi's individualized strategy, the study population was categorized into five treatment intensities of HbA1c: most intensive (≤6.5%), intensive (6.5-7.0%), less intensive (~7.0%), not intensive (7.0-8.0%), and moderated (~8.0%). The percentage of patients who met their group individualized glycemic targets was estimated as the degree of achievement of each treatment intensity. Results: The cumulative incidence rate of early microvascular, advanced microvascular, and macrovascular complications was 53%, 25%, and 34%, respectively. Besides, 78% [77.6-79%] of patients did not achieve individualized glycemic targets. Conclusion: The outcome showed poor individualized glycemic control and a high incidence of diabetes complications. Considering individualized HbA1c targets for Iranian patients with T2DM is an urgent need.
- Subjects
IRAN; DIABETES complications; REFERENCE values; GLYCOSYLATED hemoglobin; RESEARCH; CLUSTER sampling; GLYCEMIC control; CROSS-sectional method; TYPE 2 diabetes; DESCRIPTIVE statistics
- Publication
Iranian Journal of Medical Sciences, 2023, Vol 48, Issue 3, p286
- ISSN
0253-0716
- Publication type
Article
- DOI
10.30476/ijms.2022.92805.2409