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- Title
The therapeutic effect of vagus nerve stimulation on super-refractory nonconvulsive status epilepticus.
- Authors
Bora Chung; Chan Hyun Lee; Eunji Kim; Minjun Kim; Minjung Kim; Oh-Young Kwon; Do-Hyung Kim; Tae-Won Yang; Jongsoo Kang; Young-Soo Kim; Hyun Park
- Abstract
Super refractory status epilepticus (SRSE) is a condition in which status epilepticus persists despite 48 hours of anesthetic treatment. Nonconvulsive status epilepticus (NCSE) is characterized by seizures lasting more than 30 min on an electroencephalogram, with accompanying changes in behavior or consciousness without convulsions. Prompt treatment of NCSE is crucial, as delayed treatment may lead to additional brain damage and progression to convulsive status epilepticus. Although vagus nerve stimulation (VNS) has been approved as an adjunct treatment for drug-resistant epilepsy, it is rarely used to treat refractory status epilepticus. To the best of our knowledge, only two cases of NCSE treated with VNS have been reported to date, and these patients were successfully treated with VNS for NCSE caused by anti-NMDAR encephalitis. We report the case of a patient with posttraumatic epilepsy who developed super refractory-NCSE after convulsive status epilepticus and was successfully treated with VNS.
- Subjects
VAGUS nerve stimulation; STATUS epilepticus; EPILEPSY; TREATMENT effectiveness; ANTI-NMDA receptor encephalitis; TREATMENT delay (Medicine)
- Publication
Neurology Asia, 2024, Vol 29, Issue 2, p477
- ISSN
1823-6138
- Publication type
Article
- DOI
10.54029/2024wpt