We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Role of intestinal microecology in the regulation of energy metabolism by dietary polyphenols and their metabolites.
- Authors
Shaoling Lin; Zhengyu Wang; Ka-Lung Lam; Shaoxiao Zeng; Tan, Bee K.; Jiamiao Hu
- Abstract
Background: Polyphenols are a class of plant secondary metabolites with a variety of physiological functions. Polyphenols and their intestinal metabolites could greatly affect host energy metabolism via multiple mechanisms. Objective: The objective of this review was to elaborate the role of intestinal microecology in the regulatory effects of dietary polyphenols and their metabolites on energy metabolism. Methods: In this review, we illustrated the potential mechanisms of energy metabolism regulated by the crosstalk between polyphenols and intestinal microecology including intestinal microbiota, intestinal epithelial cells, and mucosal immune system. Results: Polyphenols can selectively regulate the growth of susceptible microorganisms (eg. reducing the ratio of Firmicutes to Bacteroides, promoting the growth of beneficial bacteria and inhibiting pathogenic bacteria) as well as alter bacterial enzyme activity. Moreover, polyphenols can influence the absorption and secretion of intestinal epithelial cells, and alter the intestinal mucosal immune system. Conclusion: The intestinal microecology play a crucial role for the regulation of energy metabolism by dietary polyphenols.
- Subjects
GUT microbiome; BACTEROIDES; ENERGY metabolism; EPITHELIAL cells; IMMUNE system; INTESTINAL absorption; INTESTINAL mucosa; POLYPHENOLS; SECRETION
- Publication
Food & Nutrition Research, 2019, Vol 63, p1
- ISSN
1654-6628
- Publication type
Article
- DOI
10.29219/fnr.v63.1518