After we corrected the "time zero" and included patients who were given IV antibiotics, the time-to-antibiotics was 3.49 h (IQR 1.5-16 h) after sepsis onset, and [min-max] was (0-100 h). 17.5% of the included patients received antimicrobials within 1 h of sepsis onset. The present study did not discuss this point and defined the time of sepsis onset as the time of admission to intensive care unit (ICU), which could confuse the results significantly.