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- Title
Using informatics and mobile health to improve medication safety monitoring in kidney transplant recipients.
- Authors
Taber, David J; Pilch, Nicole A; McGillicuddy, John W; Mardis, Caitlin; Treiber, Frank; Fleming, James N
- Abstract
Purpose The development, testing, and preliminary validation of a technology-enabled, pharmacist-led intervention aimed at improving medication safety and outcomes in kidney transplant recipients are described. Summary Medication safety issues, encompassing medication errors (MEs), medication nonadherence, and adverse drug events (ADEs), are a predominant cause of poor outcomes after kidney transplantation. However, a limited number of clinical trials assessing the effectiveness of technology in improving medication safety and outcomes in transplant recipients have been conducted. Through an iterative, evidence-based approach, a technology-enabled intervention aimed at improving posttransplant medication safety outcomes was developed, tested, and preliminarily validated. Early acceptability and feasibility results from a prospective, randomized controlled trial assessing the effectiveness of this system are reported here. Of the 120 patients enrolled into the trial at the time of writing, 60 were randomly assigned to receive the intervention. At a mean ± S.D. follow-up of 5.8 ± 4.0 months, there were 2 patient dropouts in the intervention group, resulting in a retention rate of 98%, which was higher than the expected 90% retention rate. Conclusion The development and deployment of a comprehensive medication safety monitoring dashboard for kidney transplant recipients is feasible and acceptable to patients in the current healthcare environment. An ongoing randomized controlled clinical trial is assessing whether such a system reduces MEs and ADRs, leading to improved patient outcomes.
- Subjects
MEDICATION error prevention; COMPUTER science; DRUGS; DRUG side effects; INFORMATION science; INTERNET; KIDNEY transplantation; PATIENT compliance; PATIENT safety; QUALITY assurance; STATISTICAL sampling; TECHNOLOGY; TELEMEDICINE; TRANSPLANTATION of organs, tissues, etc.; RANDOMIZED controlled trials; TREATMENT effectiveness; HUMAN services programs; EVALUATION of human services programs; DESCRIPTIVE statistics
- Publication
American Journal of Health-System Pharmacy, 2019, Vol 76, Issue 15, p1143
- ISSN
1079-2082
- Publication type
Article
- DOI
10.1093/ajhp/zxz115