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DNA Polymerase Diversity Reveals Multiple Incursions of Polintons During Nematode Evolution.
Published in:
Molecular Biology & Evolution, 2023, v. 40, n. 12, p. 1, doi. 10.1093/molbev/msad274
By:
- Jeong, Dae-Eun;
- Sundrani, Sameer;
- Hall, Richard Nelson;
- Krupovic, Mart;
- Koonin, Eugene V;
- Fire, Andrew Z
Publication type:
Article
High-Throughput Characterization of Cascade type I-E CRISPR Guide Efficacy Reveals Unexpected PAM Diversity and Target Sequence Preferences.
Published in:
Genetics, 2017, v. 206, n. 4, p. 1727, doi. 10.1534/genetics.117.202580
By:
- Becky Xu Hua Fu;
- Wainberg, Michael;
- Kundaje, Anshul;
- Fire, Andrew Z.
Publication type:
Article
Cas9 Variants Expand the Target Repertoire in Caenorhabditis elegans.
Published in:
Genetics, 2016, v. 202, n. 2, p. 381, doi. 10.1534/genetics.115.185041
By:
- Bell, Ryan T.;
- Fu, Becky X. H.;
- Fire, Andrew Z.
Publication type:
Article
Efficient Marker-Free Recovery of Custom Genetic Modifications with CRISPR/Cas9 in Caenorhabditis elegans.
Published in:
Genetics, 2014, v. 198, n. 3, p. 837, doi. 10.1534/genetics.114.169730
By:
- Arribere, Joshua A.;
- Bell, Ryan T.;
- Fu, Becky X. H.;
- Artiles, Karen L.;
- Hartman, Phil S.;
- Fire, Andrew Z.
Publication type:
Article
MicroRNA expression signature of human sarcomas.
Published in:
Oncogene, 2008, v. 27, n. 14, p. 2015, doi. 10.1038/sj.onc.1210836
By:
- Subramanian, S;
- Lui, W O;
- Lee, C H;
- Espinosa, I;
- Nielsen, T O;
- Heinrich, M C;
- Corless, C L;
- Fire, A Z;
- van de Rijn, M
Publication type:
Article
Intricate and Cell Type-Specific Populations of Endogenous Circular DNA (eccDNA) in Caenorhabditis elegans and Homo sapiens.
Published in:
G3: Genes | Genomes | Genetics, 2017, v. 7, n. 10, p. 3295, doi. 10.1534/g3.117.300141
By:
- Shoura, Massa J.;
- Gabdank, Idan;
- Hansen, Loren;
- Merker, Jason;
- Gotlib, Jason;
- Levene, Stephen D.;
- Fire, Andrew Z.
Publication type:
Article
Unusual DNA packaging characteristics in endoreduplicated Caenorhabditis elegans oocytes defined by in vivo accessibility to an endogenous nuclease activity.
Published in:
Epigenetics & Chromatin, 2013, v. 6, n. 1, p. 2, doi. 10.1186/1756-8935-6-37
By:
- Gu, Sam Guoping;
- Goszczynski, Barbara;
- McGhee, James D.;
- Fire, Andrew Z.
Publication type:
Article
An in vitro-identified high-affinity nucleosome-positioning signal is capable of transiently positioning a nucleosome in vivo.
Published in:
Epigenetics & Chromatin, 2010, v. 3, p. 13, doi. 10.1186/1756-8935-3-13
By:
- Gracey, Lia E.;
- Zhi-Ying Chen;
- Maniar, Jay M.;
- Valouev, Anton;
- Sidow, Arend;
- Kay, Mark A.;
- Fire, Andrew Z.
Publication type:
Article
Antibody lineages with evidence of somatic hypermutation persisting for >4 years in a South African subject with broad neutralizing activity.
Published in:
2012
By:
- Moody, M.;
- Trama, A. M.;
- Bonsignori, M.;
- Tsao, C.;
- Drinker, M. S.;
- Gurley, T. C.;
- Amos, J. D.;
- Eudailey, J. A.;
- Armand, L. C.;
- Parks, R.;
- Lloyd, K. E.;
- Wang, S.;
- Seo, K.;
- Lee, J.;
- Jackson, K. J.;
- Hoh, R.;
- Pham, T.;
- Roskin, K. M.;
- Boyd, S. D.;
- Fire, A. Z.
Publication type:
Abstract
Minicircle DNA Vectors Achieve Sustained Expression Reflected by Active Chromatin and Transcriptional Level.
Published in:
Molecular Therapy, 2013, v. 21, n. 1, p. 131, doi. 10.1038/mt.2012.244
By:
- Gracey Maniar, Lia E.;
- Maniar, Jay M.;
- Chen, Zhi-Ying;
- Lu, Jiamiao;
- Fire, Andrew Z.;
- Kay, Mark A.
Publication type:
Article
The Extragenic Spacer Length Between the 5′ and 3′ Ends of the Transgene Expression Cassette Affects Transgene Silencing From Plasmid-based Vectors.
Published in:
Molecular Therapy, 2012, v. 20, n. 11, p. 2111, doi. 10.1038/mt.2012.65
By:
- Lu, Jiamiao;
- Zhang, Feijie;
- Xu, Siqun;
- Fire, Andrew Z;
- Kay, Mark A
Publication type:
Article
A Caenorhabditis elegans RNA-Directed RNA Polymerase in Sperm Development and Endogenous RNA Interference.
Published in:
Genetics, 2009, v. 183, n. 4, p. 1297, doi. 10.1534/genetics.109.109686
By:
- Gent, Jonathan I.;
- Schvarzstein, Mara;
- Villeneuve, Anne M.;
- Sam Guoping Gu;
- Jantsch, Verena;
- Fire, Andrew Z.;
- Baudnmont, Antoine
Publication type:
Article
Transmission Dynamics of Heritable Silencing Induced by Double-Stranded RNA in Caenorhabditis elegans.
Published in:
Genetics, 2008, v. 180, n. 3, p. 1275, doi. 10.1534/genetics.108.089433
By:
- Alcazar, Rosa M.;
- Lint, Rueyling;
- Fire, Andrew Z.
Publication type:
Article
Nonsense mRNA suppression via nonstop decay.
Published in:
eLife, 2018, p. 1, doi. 10.7554/eLife.33292
By:
- Arribere, Joshua A.;
- Fire, Andrew Z.
Publication type:
Article
Type III CRISPR-Cas systems can provide redundancy to counteract viral escape from type I systems.
Published in:
eLife, 2017, p. 1, doi. 10.7554/eLife.27601.001
By:
- Silas, Sukrit;
- Lucas-Elio, Patricia;
- Jackson, Simon A.;
- Aroca-Crevillén, Alejandra;
- Hansen, Loren L.;
- Fineran, Peter C.;
- Fire, Andrew Z.;
- Sánchez-Amat, Antonio
Publication type:
Article
Deconvolution of nucleic-acid length distributions: a gel electrophoresis analysis tool and applications.
Published in:
Nucleic Acids Research, 2019, v. 47, n. 16, p. e92, doi. 10.1093/nar/gkz534
By:
- Ziraldo, Riccardo;
- Shoura, Massa J;
- Fire, Andrew Z;
- Levene, Stephen D
Publication type:
Article
Distinct patterns of Cas9 mismatch tolerance in vitro and in vivo.
Published in:
Nucleic Acids Research, 2016, v. 44, n. 11, p. 5365, doi. 10.1093/nar/gkw417
By:
- Fu, Becky X. H.;
- Onge, Robert P. St.;
- Fire, Andrew Z.;
- Smith, Justin D.
Publication type:
Article
Landscape of target:guide homology effects on Cas9-mediated cleavage.
Published in:
Nucleic Acids Research, 2014, v. 42, n. 22, p. 13778, doi. 10.1093/nar/gku1102
By:
- Becky Xu Hua Fu;
- Hansen, Loren L.;
- Artiles, Karen L.;
- Nonet, Michael L.;
- Fire, Andrew Z.
Publication type:
Article
Intron and gene size expansion during nervous system evolution.
Published in:
BMC Genomics, 2020, v. 21, n. 1, p. 1, doi. 10.1186/s12864-020-6760-4
By:
- McCoy, Matthew J.;
- Fire, Andrew Z.
Publication type:
Article
Gene Silencing by Double-Stranded RNA (Nobel Lecture).
Published in:
Angewandte Chemie International Edition, 2007, v. 46, n. 37, p. 6966, doi. 10.1002/anie.200701979
By:
- Fire, Andrew Z.
Publication type:
Article
Co-evolution of a broadly neutralizing HIV-1 antibody and founder virus.
Published in:
Nature, 2013, v. 496, n. 7446, p. 469, doi. 10.1038/nature12053
By:
- Liao, Hua-Xin;
- Lynch, Rebecca;
- Zhou, Tongqing;
- Gao, Feng;
- Alam, S. Munir;
- Boyd, Scott D.;
- Fire, Andrew Z.;
- Roskin, Krishna M.;
- Schramm, Chaim A.;
- Zhang, Zhenhai;
- Zhu, Jiang;
- Shapiro, Lawrence;
- Becker, Jesse;
- Benjamin, Betty;
- Blakesley, Robert;
- Bouffard, Gerry;
- Brooks, Shelise;
- Coleman, Holly;
- Dekhtyar, Mila;
- Gregory, Michael
Publication type:
Article
Determinants of nucleosome organization in primary human cells.
Published in:
Nature, 2011, v. 474, n. 7352, p. 516, doi. 10.1038/nature10002
By:
- Valouev, Anton;
- Johnson, Steven M.;
- Boyd, Scott D.;
- Smith, Cheryl L.;
- Fire, Andrew Z.;
- Sidow, Arend
Publication type:
Article
A streamlined tethered chromosome conformation capture protocol.
Published in:
BMC Genomics, 2016, v. 17, p. 1, doi. 10.1186/s12864-016-2596-3
By:
- Gabdank, Idan;
- Ramakrishnan, Sreejith;
- Villeneuve, Anne M.;
- Fire, Andrew Z.
Publication type:
Article
Gene silencing by double-stranded RNA.
Published in:
Cell Death & Differentiation, 2007, v. 14, n. 12, p. 1998, doi. 10.1038/sj.cdd.4402253
By:
- Fire, A. Z.
Publication type:
Article
Regulation of apoptosis by C. elegans CED-9 in the absence of the C-terminal transmembrane domain.
Published in:
Cell Death & Differentiation, 2007, v. 14, n. 11, p. 1925, doi. 10.1038/sj.cdd.4402215
By:
- Tan, F. J.;
- Fire, A. Z.;
- Hill, R. B.
Publication type:
Article
Measurement and Clinical Monitoring of Human Lymphocyte Clonality by Massively Parallel V-D-J Pyrosequencing.
Published in:
Science Translational Medicine, 2009, v. 1, n. 12, p. 1, doi. 10.1126/scitranslmed.3000540
By:
- Boyd, Scott D.;
- Marshall, Eleanor L.;
- Merker, Jason D.;
- Maniar, Jay M.;
- Zhang, Lyndon N.;
- Sahaf, Bita;
- Jones, Carol D.;
- Simen, Birgitte B.;
- Hanczaruk, Bozena;
- Nguyen, Khoa D.;
- Nadeau, Kari C.;
- Egholm, Michael;
- Miklos, David B.;
- Zehnder, James L.;
- Fire, Andrew Z.
Publication type:
Article
A pyrosequencing-tailored nucleotide barcode design unveils opportunities for large-scale sample multiplexing.
Published in:
Nucleic Acids Research, 2007, v. 35, n. 19, p. e130, doi. 10.1093/nar/gkm760
By:
- Parameswaran, Poornima;
- Jalili, Roxana;
- Tao, Li;
- Shokralla, Shadi;
- Gharizadeh, Baback;
- Ronaghi, Mostafa;
- Fire, Andrew Z.
Publication type:
Article
Competition between ADAR and RNAi pathways for an extensive class of RNA targets.
Published in:
Nature Structural & Molecular Biology, 2011, v. 18, n. 10, p. 1094, doi. 10.1038/nsmb.2129
By:
- Wu, Diane;
- Lamm, Ayelet T;
- Fire, Andrew Z
Publication type:
Article
Capped small RNAs and MOV10 in human hepatitis delta virus replication.
Published in:
Nature Structural & Molecular Biology, 2008, v. 15, n. 7, p. 714, doi. 10.1038/nsmb.1440
By:
- Haussecker, Dirk;
- Cao, Dan;
- Huang, Yong;
- Parameswaran, Poornima;
- Fire, Andrew Z.;
- Kay, Mark A.
Publication type:
Article

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