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- Title
Active surveillance of adverse events following immunization in primary health care.
- Authors
Batista, Emily Caroline Cardoso; Ferreira, Ana Paula; de Oliveira, Valéria Conceição; Amaral, Gabriela Gonçalves; de Jesus, Renato Fernando; Quintino, Nayara Dornela; Viegas, Selma Maria da Fonseca; de Azevedo Guimarães, Eliete Albano
- Abstract
Objective: To describe the active surveillance of adverse events following immunization, their incidence and associated factors in a municipality of Minas Gerais, Brazil. Methods: This is a prospective cohort conducted in Primary Health Care between 2017 and 2018. A total of 384 individuals who received vaccines were followed up, excluding those who had previous adverse events. At baseline, sociodemographic, health and vaccination history information and, in follow-up, the characteristics of adverse events and epidemiological surveillance actions were collected. The incidence rate of adverse events was estimated, and the chi-square test, poisson regression and Hosmer-Lemeshow test were performed. Results: The incidence of adverse events was 13.36 cases/100,000 doses of vaccines (95% confidence interval: 13.34-13.38), with a higher incidence in children under 5 years of age. The most frequent adverse events were local pain, redness, hardening, followed by fever and persistent crying. Among the factors associated with the occurrence of adverse events, receiving tetanus and diffrhyphria vaccine (relative risk: 7.9; 95% confidence interval: 2.77-12.46) and intramuscular administration were considered at risk (relative risk: 6.1; 95% confidence interval: 2.55-14.63). Nursing professionals' conduct, considering the guidelines on the vaccines received, increased adverse event reporting (relative risk: 3.4; 95% confidence interval: 1.53-7.68). Conclusion: The study allowed to know factors that favor the occurrence of adverse events. There is evidence that conducts adopted by nursing professionals in immunization rooms may avoid underreporting of adverse events following immunization.
- Subjects
BRAZIL; PUBLIC health surveillance; IMMUNIZATION; CONFIDENCE intervals; PRIMARY health care; SOCIOECONOMIC factors; CHI-squared test; DRUG side effects; LONGITUDINAL method
- Publication
Acta Paulista de Enfermagem, 2021, Vol 34, Issue 4, p1
- ISSN
0103-2100
- Publication type
Article
- DOI
10.37689/actaape/2021AO002335