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- Title
Lesion index: a novel guide in the path of successful pulmonary vein isolation.
- Authors
Dello Russo, Antonio; Fassini, Gaetano M.; Casella, Michela; Romanelli, Elena; Pala, Salvatore; Riva, Stefania; Catto, Valentina; Moltrasio, Massimo; Tundo, Fabrizio; Zucchetti, Martina; Majocchi, Benedetta; Dessanai, Maria Antonietta; Pizzamiglio, Francesca; Vettor, Giulia; Ribatti, Valentina; Gasperetti, Alessio; Cellucci, Selene; Negro, Gabriele; Sicuso, Rita; Carbucicchio, Corrado
- Abstract
<bold>Purpose: </bold>Previous studies indicate force time integral (FTI) as a radiofrequency (RF) lesion quality marker, while not considering power supply. Tacticath™ Quartz catheter provides Lesion index (LSI), a lesion quality marker derived by contact force (CF), power supply, and RF time combined. Our aim is to assess LSI and FTI correlation and a LSI-related cutoff of atrial fibrillation (AF) recurrences 12 months after pulmonary vein isolation (PVI).<bold>Methods: </bold>We retrospectively enrolled 37 patients who underwent RF ablation using Tacticath™ Quartz catheter. AF recurrence rate was evaluated 3, 6, and 12 months after PVI procedure.<bold>Results: </bold>AF recurrence was detected in 32% of patients. FTI mean value was significantly lower in left superior pulmonary vein (LSPV: 256 ± 86 gs vs 329 ± 117 gs, p = 0.05) and right inferior pulmonary vein (RIPV: 253 ± 128 gs vs 394 ± 123 gs p = 0.006) in patients with AF recurrences; no significant differences were found in right superior pulmonary vein (RSPV) and left inferior pulmonary vein (LIPV). LSI instead was significantly higher for all veins in patients without AF recurrences: LSPV (5.2 ± 0.7 vs 4.6 ± 0.8, p = 0.03), LIPV (5.0 ± 0.8 vs 4.5 ± 0.6, p = 0.04), RSPV (5.5 ± 0.6 vs 5.1 ± 0.6, p = 0.05), and RIPV (5.5 ± 0.7 vs 4.7 ± 0.8, p = 0.006). Receiver operator characteristic curve suggests 5.3 as LSI overall cutoff value predicting freedom from disease at 1-year follow-up.<bold>Conclusions: </bold>Our preliminary data suggest that a LSI mean value higher than 5.3 can be considered a good predictor of AF freedom at 1-year follow-up.
- Subjects
ATRIAL fibrillation; PULMONARY veins; POWER resources; FOLLOW-up studies (Medicine); VEINS; ECHOCARDIOGRAPHY; ELECTROCARDIOGRAPHY; HEART function tests; DISEASE relapse; RETROSPECTIVE studies
- Publication
Journal of Interventional Cardiac Electrophysiology, 2019, Vol 55, Issue 1, p27
- ISSN
1383-875X
- Publication type
journal article
- DOI
10.1007/s10840-018-0487-z