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- Title
阿托品在保留自主呼吸无痛纤维支气管镜检查中的应用.
- Authors
刘光顺; 向旭东; 吕志勇; 周 敏; 汪亚宏
- Abstract
bjective To study the role of atropine in spontaneous breathing painless fiberoptic bronchoscopy. Methods Forty cases of patients scheduled for receivepainless fiberoptic bronchoscopy were randomly divided into 2 groups,with 20 cases in each group.The patients in the control group (group C) were gven the intravenous anesthesia with sufentanil 0.1 μg/kg,dexmedetomidine 0.2 μg/kg,propofol 1 mg/kg,remifentanil 0.2 μg/kg,propofol 1 mg/kg,then endotracheal fiberoptic bronchoscopy were conducted cooperating with the endotracheal surface anesthesia.An extra propofol 0.4 mg/kg was given when choking cough or body moving occurred.The patients in the observation group (group S) were given atropine 0.006 mg/kg intravenous injection,the subsequent processing was the same as for group C. The changes of vital signs at different points during the perioperative period,the time of operation,anesthesia recovery and leaving operation room,the excellent and good rate for anesthesia,the number of cases of propofol supplementation and use of vasoactive drugs,the incidence of intraoperative respiratory adverse events and postoperative adverse events were observed and compared between the two groups. Results The levels of HR,MAP and SpO2 had no significant different between the two groups on T1 (P > 0.05),those of group S were significantly higher than group C on T2 (P < 0.05),the levels of HR and MAP on T2 were significantly lower than those on T1 in group C (P < 0.05),the rate of excellent and good of anesthesia of group S was significantly higher than that of group C (P < 0.05),the time of anesthesia recovery and leaving the operation room of group S were significantly lower than that of group C ( P < 0.01),the number of cases of intraoperative propofol supplementation and use of vasoactive drugs of group S were significantly lower than those of group C (P < 0.05),the incidence of intraoperative respiratory adverse events of group S was significantly lower than that of group C (P < 0.05). Conclusion Atropine can improve the safety of the anesthesia of preserving spontaneous breathing for painless fiberoptic bronchoscopy.
- Publication
Journal of Kunming Medical University / Kunming Yike Daxue Xuebao, 2021, Vol 42, Issue 9, p71
- ISSN
2095-610X
- Publication type
Article
- DOI
10.12259/j.issn.2095-610X.S20210912