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- Title
Mniejsze rozpowszechnienie niedoboru witaminy D wśród dziewcząt z jadłowstrętem psychicznym niż u dziewcząt zdrowych.
- Authors
Ducki, Czeław; Oświęcimska, Joanna; Mazur, Bogdan; Ziora-Jakutowicz, Karolina; Jarzumbek, Anna; Klimaszewska-Adamus, Karolina; Piątek-Dąbrowska, Katarzyna; Ziora, Katarzyna
- Abstract
Introduction. Available studies of vitamin D (25OHD) serum levels concentrations in patients suffering from anorexia nervosa (AN) were conducted mostly to women. So far the results are divergent. Among women with AN some authors showed lower concentrations of vitamin D in the blood, while others higher concentrations when compared to healthy subjects (HS). Aim of the study. 1. Assessment of 25OHD concentrations in blood serum in women suffering AN compared to healthy subjects (HS) 2. Comparison of deficiency prevalence of vitamin D in women with AN, compared to the HS. 3. Analysis the relationship between 25OHD levels in the blood and body weight, BMI and duration of the disease in women with AN. Material and methods. The study included 88 girls, including in 53 of AN (mean age: 13.0 ±4.2 years; body weight: 39.8 ± 1.6 kg; BMI-SDS: - 2.28 ± 0.26) and in 35 HS (mean age: 13.7 ±0.6 years; body weight: 52.4 ±2.1; BMI-SDS: 0.26 ±0.23). All patients have been screened for Ca, Ca++, P, ALP and 25OHD (vit. D total) concentration in blood serum. Results. Mean concentration of Ca, Ca++, P and ALP in blood serum in both groups were normal, and 25OHD concentration was reduced compared to standard norm. In girls with AN lower concentration of Ca, P and ALP and higher concentration of Ca++ in serum (p <0.001) was reported comparing to HS. Mean 25OHD concentrations in serum AN group were statistically significantly higher than HS group (p <0.05). Lower prevalence of 25OHD deficiency was demonstrated in patients with AN than HS. 19.2% of girls with AN and 5.7% of HS have 25OHD concentration higher than 30 ng/ml. There was no statistically significant correlation observed between serum 25OHD in the blood and the subjects' age, weight, BMI and BMI-SDS or disease duration in the AN group. Conclusions. 1. In Polish girls suffering from AN we have observed reduced resources of vitamin D in the body, although the prevalence of deep deficit of this vitamin is lower than in healthy subjects. 2. It is recommended to measure concentrations of vitamin D in the blood of all patients suffering from anorexia nervosa and diminish vitamin D deficiency through supplementation.
- Publication
Pediatric Endocrinology / Endokrynologia Pediatryczna, 2015, Vol 14, Issue 3, p15
- ISSN
1730-0282
- Publication type
Article