We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Characterization and Function of MicroRNA٭s in Plants.
- Authors
Wei-wei Liu; Jun Meng; Jun Cui; Yu-shi Luan
- Abstract
MicroRNAs, a group of non-coding RNA molecules, play essential roles in a wide range of cellular processes in different molecules, cells, and organisms. In plants, microRNAs are a class of 20- to 24-nucleotides endogenous small RNAs that repress gene expression. The microRNA guide strand (miRNA) and its complementary strand (miRNA٭) both originate from the miRNA/miRNA٭ duplex. Generally, the guide strands act as post-transcriptional regulators that suppress gene expression by cleaving their target mRNA transcripts, whereas the complementary strands were thought to be degraded as ‘passenger strands.’ However, the complementary strand has been confirmed to possess significant biological functionality in recent reports. In this review, we summarized the binding characteristics of the miRNA٭ strands with ARGONAUTE proteins, their tissue-specific accumulations and their biological functions, illustrating the essential roles of miRNA٭S in biological processes and therefore providing directions for further exploration.
- Subjects
MICRORNA; NON-coding RNA; PLANTS
- Publication
Frontiers in Plant Science, 2017, p1
- ISSN
1664-462X
- Publication type
Article
- DOI
10.3389/fpls.2017.02200