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- Title
Kronik Spontan Ürtikerli Hastalarda Kronik Yaygın Ağrı Sıklığı ve Yaşam Kalitesi Üzerine Etkisi.
- Authors
Ertaş, Ragıp; Erol, Kemal
- Abstract
Objective: Chronic spontaneous urticaria (CSU) is a chronic, common and debilitating disease and associated with severely impaired quality of life (QoL). The main aim of this study is to explore the presence of Chronic Widespread Pain (CWP) in patients with CSU and to reveal the possible associations between CWP and CSU on the clinical features, laboratory markers and urticaria activity scores with QoL. Methods: There were assessed the 91 patients with CSU for CWP in a tertiary outpatient clinic. CWP (pain in four or more out of five bodily regions, i.e., the four quadrants and axially at least for three months) was defined in a rheumatology outpatient clinic in patients with CSU. We also analyzed the test results of anti-nuclear antibody (ANA), blood sedimentation rate, CRP (C-reactive protein), B12, total IgE, and anti-TPO. Patients were specified for their onset and duration of disease, comorbidities, the occurrence of angioedema and history of atopy, and nocturnal pruritus with disturbed sleep. Patients disease activity were detected by the urticaria control test (UCT), urticaria activity score (UAS) and visual analog scale of physician and patient's global assessment. Furthermore, patients completed a questionnaire to assess the quality of life (QoL) for dermatologic diseases. Results: 91 patients with CSU assigned for CWP, 23 (25.3%) were positive. CWP + patients with CSU had significantly higher physician global assessment score (p=0.003), Patients global assessment score (p=0.005), UAS (p=0.046), dermatologic QoL (p<0.001) and lower UCT (p=0.005) scores. Nine of 23 CWP + patients had asthma (39.1%) as a comorbidity (p=0.008). Conclusion: The presence of CWP in patients with urticaria may have a negative impact on the quality of life of the patients and disease scores.
- Subjects
AUTOANTIBODY analysis; URTICARIA; IMMUNOGLOBULIN analysis; AGE factors in disease; ANGIONEUROTIC edema; ASTHMA; BIOMARKERS; BLOOD sedimentation; C-reactive protein; CHRONIC diseases; CHRONIC pain; OUTPATIENT services in hospitals; OXIDOREDUCTASES; QUALITY of life; QUESTIONNAIRES; RHEUMATOLOGY; VITAMIN B12; COMORBIDITY; PAIN measurement; VISUAL analog scale; DISEASE duration; TERTIARY care; CHEMICAL inhibitors; DIAGNOSIS
- Publication
Konuralp Medical Journal / Konuralp Tip Dergisi, 2019, Vol 11, Issue 1, p101
- ISSN
1309-3878
- Publication type
Article
- DOI
10.18521/ktd.520277