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- Title
Is Dermatitis Herpetiformis a Gluten-Sensitive Enteropathy?
- Authors
Savilahti, Erkki; Reuneda, Timo
- Abstract
In 1966, scientists found an enteropathy similar to that in celiac disease (CD) in the majority of their patients with dermatitis herpetiformis (DH). This prompted the successful trial to treat DH with the accepted remedy of CD, the gluten-free diet, further documenting the close relationship of these two conditions. The presence of enteropathy, the response to a gluten-free diet, and other associations with CD are seen only in those patients with DH having granular immunoglobulin A deposits in the skin. About two-thirds of patients with DH have severe jejunal lesions characterized by villous atrophy together with the crypt hyperplasia present in active CD cases.
- Subjects
DERMATITIS herpetiformis; GLUTEN; INTESTINAL diseases; PATIENTS; CELIAC disease; GLUTEN-free diet; HYPERPLASIA
- Publication
International Journal of Dermatology, 1990, Vol 29, Issue 10, p706
- ISSN
0011-9059
- Publication type
Editorial
- DOI
10.1111/j.1365-4362.1990.tb03772.x