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- Title
Oral Manifestations, Dental Management and Challenges after Bone Marrow Graft.
- Authors
Dalirsani, Z.; Delavarian, Z.; Pakfetrat, A.; Amirchaghmaghi, M.; Mozaffari, P. Mosannen
- Abstract
Background: Dentists have some challenges in the treatment of patients after bone marrow graft. Some- times, they need some emergency dental treatments or are consulted for oral complications post-graft. Objective/Methods: In this paper, we discuss about oral manifestations and dental management after bone marrow graft. Results: Because of leucopenia or thrombocytopenia due to immunosuppressive drugs in these patients, they are exposed to infection or bleeding during dental treatments. Conclusion: If the count of platelets is below 50,000/ µL, elective dental treatments should be postponed and platelet transfusion is necessary for emergency procedures. If the white blood cell count falls below 2000/ µL and neutrophil count is below 1000/µL, therapy needs multi-doses of prophylactic antibiotics. Furthermore, some oral presentations in these patients should be diagnosed properly. For example, acute necrotizing ulcerative gingivitis on palatal or gingival mucosa presents as punched out ulcer; patients with this ulcer complain of tooth pain. Other oral manifestations include oral ulcers, candidiasis, and spontaneous gingival bleeding. Immunosuppressive drugs lead to oral mucositis and consequently malnutrition. Treatment of oral lesions consists of palliative therapy, anti-fungal, local or systemic anti-inflammatory drugs. Early diagnosis of oral lesions and appropriate treatments decrease patients' suffer and improve their nutrition and prevent complications of malnutrition.
- Subjects
BONE marrow transplantation; TRANSPLANTATION of organs, tissues, etc.; BLOOD transfusion
- Publication
International Journal of Organ Transplantation Medicine, 2016, Vol 7, Issue 2, p126
- ISSN
2008-6490
- Publication type
Abstract