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- Title
The mRNA puzzle: Intron retention under stress.
- Authors
Arribas-Hernández, Laura
- Abstract
This article discusses the process of alternative splicing (AS) in nucleated cells, where cells can choose which parts of a transcript to skip or keep, resulting in multiple messages from the same DNA. The study focuses on the role of protein arginine methyltransferases (PRMTs) in AS regulation in plants, specifically the methylation of splicing factor LSM4 by PRMT5. The researchers found that LSM4 methylation is important for growth and circadian rhythm in plants, and it may play a role in stress responses. The study also identified several genes involved in stress responses that are affected by LSM4 methylation.
- Subjects
PROTEIN arginine methyltransferases; ALTERNATIVE RNA splicing; MESSENGER RNA; INTRONS
- Publication
Plant Cell, 2024, Vol 36, Issue 6, p2057
- ISSN
1040-4651
- Publication type
Article
- DOI
10.1093/plcell/koae093