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- Title
Potencial antimicrobiano de seis plantas do semiárido paraibano contra bactérias relacionadas à infecção endodôntica.
- Authors
Lira de Souza Sales Rocha, Eveline Angélica; Rolim de Carvalho, Anne Virgynnia Oliveira; Alves de Andrade, Susana Régis; Dantas de Medeiros, Ana Cláudia; de Brito Melo Trovão, Dilma Maria; Melo de Brito Costa, Edja Maria
- Abstract
In the face of an increasing range of microorganisms known to be resistant to antimicrobial substances, various herbal extracts have been screened in order to find new compounds with recognized antimicrobial activity. In particular, this study was carried out to assess the antimicrobial activity of such extracts on bacteria related to endodontic infection. Hydroalcoholic extracts of the species Syderoxylum obtusifolium Roem and Schult (quixabeira), Bauhinia foricata Linn (mororó) Anadenanthera colubrina Brenan (angico), Spondias tuberosa Arruda (umbuzeiro), Tabebuia pentaphylla Vell. (ipê rosa) and Guapira graciliflora Mart. (joão-mole), were tested against Enterococcus faecalis, Staphylococcus aureus and Escherichia coli. The antimicrobial assays were performed by the disk agar diffusion and broth microdilution methods. All extracts analyzed showed antimicrobial activity against at least one bacterial species. The best results were obtained with T. pentaphylla and G. graciliflora, which showed activity against all tested strains; specifically, that of T. pentaphylla against S. aureus, at a concentration of 0.78µL/µL, and of G. graciliflora bark against E. faecalis, at a concentration of 6.25µL/µL, should be highlighted. The results indicate that extracts of these plants may be promising for the study and development of new antimicrobials for endodontic use.
- Subjects
DRUG resistance in bacteria; ANTI-infective agents; BAUHINIA; SPONDIAS; ANADENANTHERA
- Publication
Revista de Ciências Farmacêuticas Básica e Aplicada, 2013, Vol 34, Issue 3, p351
- ISSN
1808-4532
- Publication type
Article