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- Title
Evaluation of a Premixed Insulin Analog Suspension in Japanese People with Type 2 Diabetes and the Clinical Importance of Improved Injection Techniques: A Cross-Sectional Pilot Study.
- Authors
Suzuki, Kunihiro; Aoki, Chie; Kato, Kanako; Shimizu, Masanori; Sakurai, Shintaro; Yanagi, Kazunori; Kuroda, Hisamoto; Aso, Yoshimasa
- Abstract
Introduction: Patients with type 2 diabetes, who live in Asian countries, often use premixed insulin analogs. However, if these solutions are insufficiently mixed prior to use, patients will receive inaccurate doses of intermediate- and/or short-acting insulin, which could affect diabetes control. This study aimed to determine whether insulin users were correctly resuspending premixed insulin analog solutions prior to use. Methods: We investigated whether Japanese patients with type 2 diabetes were correctly resuspending their premixed insulin analog solutions by assessing the optical densities (ODs) of the solutions. Results: Among 476 patients who used premixed insulin analogs, we found that the ODs of residual insulin differed significantly from the control values, particularly for high-mix insulin suspensions. Conclusion: Our findings suggest that patients should be educated about the importance of properly resuspending these insulin analog solutions prior to use. Trial Registration: University Hospital Medical Information Network (UMIN No. 000022329).
- Subjects
INSULIN; PROINSULIN; PEPTIDE hormones; PEPTIDES; CARBOHYDRATE intolerance; ENDOCRINE diseases
- Publication
Diabetes Therapy, 2017, Vol 8, Issue 2, p445
- ISSN
1869-6953
- Publication type
Report
- DOI
10.1007/s13300-017-0228-9