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- Title
Can All Major Ros Forming Sites of the Respiratory Chain Be Activated by High FADH<sub>2</sub>/NADH Ratios?
- Authors
Schönfeld, Peter
- Abstract
The article offers information on impact of flavin adenine dinucleotide/ nicotinamide adenine dinucleotide (FADH2/NADH) on the reactive oxygen species (ROS) forming sites of respiratory chain. Topics discussed include production of harmful ROS by adenosine triphostate (ATP) mitochondria; mitochondrial oxidation shifts from substrates with low FADH2/NADH to those with high FADH2/NADH ratio; and fasting enhances the risk of liver damage by oxidative stress.
- Subjects
FLAVIN adenine dinucleotide; ACTIVE oxygen in the body; RESPIRATION; ADENOSINE triphosphate analysis; OXIDATION of DNA; NICOTINAMIDE adenine dinucleotide phosphate; FASTING
- Publication
BioEssays, 2019, Vol 41, Issue 1, pN.PAG
- ISSN
0265-9247
- Publication type
Article
- DOI
10.1002/bies.201800225