OpenURL Connection Search

Select item for more details and to access through your institution.

Discovery of a Potent Degrader for Fibroblast Growth Factor Receptor 1/2.
Published in:
Angewandte Chemie, 2021, v. 133, n. 29, p. 16041, doi. 10.1002/ange.202101328
By:
- Du, Guangyan;
- Jiang, Jie;
- Wu, Qibiao;
- Henning, Nathaniel J.;
- Donovan, Katherine A.;
- Yue, Hong;
- Che, Jianwei;
- Lu, Wenchao;
- Fischer, Eric S.;
- Bardeesy, Nabeel;
- Zhang, Tinghu;
- Gray, Nathanael S.
Publication type:
Article
Titelbild: Lokale Deuterierung ermöglicht NMR‐Messung von Methylgruppen in Proteinen aus eukaryotischen und Zell‐freien Expressionssystemen (Angew. Chem. 25/2021).
Published in:
Angewandte Chemie, 2021, v. 133, n. 25, p. 13801, doi. 10.1002/ange.202105426
By:
- Dubey, Abhinav;
- Stoyanov, Nikolay;
- Viennet, Thibault;
- Chhabra, Sandeep;
- Elter, Shantha;
- Borggräfe, Jan;
- Viegas, Aldino;
- Nowak, Radosław P.;
- Burdzhiev, Nikola;
- Petrov, Ognyan;
- Fischer, Eric S.;
- Etzkorn, Manuel;
- Gelev, Vladimir;
- Arthanari, Haribabu
Publication type:
Article
Lokale Deuterierung ermöglicht NMR‐Messung von Methylgruppen in Proteinen aus eukaryotischen und Zell‐freien Expressionssystemen.
Published in:
Angewandte Chemie, 2021, v. 133, n. 25, p. 13902, doi. 10.1002/ange.202016070
By:
- Dubey, Abhinav;
- Stoyanov, Nikolay;
- Viennet, Thibault;
- Chhabra, Sandeep;
- Elter, Shantha;
- Borggräfe, Jan;
- Viegas, Aldino;
- Nowak, Radosław P.;
- Burdzhiev, Nikola;
- Petrov, Ognyan;
- Fischer, Eric S.;
- Etzkorn, Manuel;
- Gelev, Vladimir;
- Arthanari, Haribabu
Publication type:
Article
Mutant‐Selective Allosteric EGFR Degraders are Effective Against a Broad Range of Drug‐Resistant Mutations.
Published in:
Angewandte Chemie, 2020, v. 132, n. 34, p. 14589, doi. 10.1002/ange.202003500
By:
- Jang, Jaebong;
- To, Ciric;
- De Clercq, Dries J. H.;
- Park, Eunyoung;
- Ponthier, Charles M.;
- Shin, Bo Hee;
- Mushajiang, Mierzhati;
- Nowak, Radosław P.;
- Fischer, Eric S.;
- Eck, Michael J.;
- Jänne, Pasi A.;
- Gray, Nathanael S.
Publication type:
Article
Development of CDK2 and CDK5 Dual Degrader TMX‐2172.
Published in:
Angewandte Chemie, 2020, v. 132, n. 33, p. 13969, doi. 10.1002/ange.202004087
By:
- Teng, Mingxing;
- Jiang, Jie;
- He, Zhixiang;
- Kwiatkowski, Nicholas P.;
- Donovan, Katherine A.;
- Mills, Caitlin E.;
- Victor, Chiara;
- Hatcher, John M.;
- Fischer, Eric S.;
- Sorger, Peter K.;
- Zhang, Tinghu;
- Gray, Nathanael S.
Publication type:
Article
Development of Dual and Selective Degraders of Cyclin‐Dependent Kinases 4 and 6.
Published in:
Angewandte Chemie, 2019, v. 131, n. 19, p. 6387, doi. 10.1002/ange.201901336
By:
- Jiang, Baishan;
- Wang, Eric S.;
- Donovan, Katherine A.;
- Liang, Yanke;
- Fischer, Eric S.;
- Zhang, Tinghu;
- Gray, Nathanael S.
Publication type:
Article
Can portable glucose and lactate meters be a useful tool in quantifying stress of juvenile Chinook salmon?
Published in:
Conservation Physiology, 2023, v. 11, n. 1, p. 1, doi. 10.1093/conphys/coad046
By:
- Vaage, Benjamin M;
- Liss, Stephanie A;
- Fischer, Eric S;
- Khan, Fenton;
- Hughes, James S
Publication type:
Article
Functional regulation of the DNA damage-recognition factor DDB2 by ubiquitination and interaction with xeroderma pigmentosum group C protein.
Published in:
Nucleic Acids Research, 2015, v. 43, n. 3, p. 1700, doi. 10.1093/nar/gkv038
By:
- Matsumoto, Syota;
- Fischer, Eric S.;
- Yasuda, Takeshi;
- Dohmae, Naoshi;
- Iwai, Shigenori;
- Mori, Toshio;
- Nishi, Ryotaro;
- Yoshino, Ken-ichi;
- Sakai, Wataru;
- Hanaoka, Fumio;
- Thomä, Nicolas H.;
- Sugasawa, Kaoru
Publication type:
Article
Small molecule degraders of the hepatitis C virus protease reduce susceptibility to resistance mutations.
Published in:
Nature Communications, 2019, v. 10, n. 1, p. N.PAG, doi. 10.1038/s41467-019-11429-w
By:
- de Wispelaere, Mélissanne;
- Yang, Priscilla L.;
- Du, Guangyan;
- Donovan, Katherine A.;
- Zhang, Tinghu;
- Nowak, Radosław P.;
- Fischer, Eric S.;
- Gray, Nathanael S.;
- Eleuteri, Nicholas A.;
- Yuan, Jingting C.;
- Kalabathula, Joann
Publication type:
Article
How Small Can We Go? Evaluating Survival, Tag Retention, and Growth of Juvenile Chinook Salmon Implanted with a New Acoustic Microtag.
Published in:
North American Journal of Fisheries Management, 2019, v. 39, n. 6, p. 1329, doi. 10.1002/nafm.10367
By:
- Fischer, Eric S.;
- Blackburn, Shannon E.;
- Liss, Stephanie A.;
- Hughes, James S.;
- Li, Huidong;
- Deng, Zhiqun Daniel
Publication type:
Article
Front Cover: Development and Characterization of Selective FAK Inhibitors and PROTACs with In Vivo Activity (ChemBioChem 19/2023).
Published in:
ChemBioChem, 2023, v. 24, n. 19, p. 1, doi. 10.1002/cbic.202300535
By:
- Koide, Eriko;
- Mohardt, Mikaela L.;
- Doctor, Zainab M.;
- Yang, Annan;
- Hao, Mingfeng;
- Donovan, Katherine A.;
- Kuismi, Christina C.;
- Nelson, Alissa J.;
- Abell, Kathryn;
- Aguiar, Mike;
- Che, Jianwei;
- Stokes, Matthew P.;
- Zhang, Tinghu;
- Aguirre, Andrew J.;
- Fischer, Eric S.;
- Gray, Nathanael S.;
- Jiang, Baishan;
- Nabet, Behnam
Publication type:
Article
Development and Characterization of Selective FAK Inhibitors and PROTACs with In Vivo Activity.
Published in:
ChemBioChem, 2023, v. 24, n. 19, p. 1, doi. 10.1002/cbic.202300141
By:
- Koide, Eriko;
- Mohardt, Mikaela L.;
- Doctor, Zainab M.;
- Yang, Annan;
- Hao, Mingfeng;
- Donovan, Katherine A.;
- Kuismi, Christina C.;
- Nelson, Alissa J.;
- Abell, Kathryn;
- Aguiar, Mike;
- Che, Jianwei;
- Stokes, Matthew P.;
- Zhang, Tinghu;
- Aguirre, Andrew J.;
- Fischer, Eric S.;
- Gray, Nathanael S.;
- Jiang, Baishan;
- Nabet, Behnam
Publication type:
Article
Discovery of Potent Degraders of the Dengue Virus Envelope Protein.
Published in:
Advanced Science, 2024, v. 11, n. 40, p. 1, doi. 10.1002/advs.202405829
By:
- Li, Zhengnian;
- Liu, Han‐Yuan;
- He, Zhixiang;
- Chakravarty, Antara;
- Golden, Ryan P.;
- Jiang, Zixuan;
- You, Inchul;
- Yue, Hong;
- Donovan, Katherine A.;
- Du, Guangyan;
- Che, Jianwei;
- Tse, Jason;
- Che, Isaac;
- Lu, Wenchao;
- Fischer, Eric S.;
- Zhang, Tinghu;
- Gray, Nathanael S.;
- Yang, Priscilla L.
Publication type:
Article
Proteomics‐Based Discovery of First‐in‐Class Chemical Probes for Programmed Cell Death Protein 2 (PDCD2).
Published in:
Angewandte Chemie, 2023, v. 135, n. 43, p. 1, doi. 10.1002/ange.202308292
By:
- Ji, Wenzhi;
- Byun, Woong Sub;
- Lu, Wenchao;
- Zhu, Xijun;
- Donovan, Katherine A.;
- Dwyer, Brendan G.;
- Che, Jianwei;
- Yuan, Linjie;
- Abulaiti, Xianmixinuer;
- Corsello, Steven M.;
- Fischer, Eric S.;
- Zhang, Tinghu;
- Gray, Nathanael S.
Publication type:
Article
Targeting the Dark Lipid Kinase PIP4K2C with a Potent and Selective Binder and Degrader.
Published in:
Angewandte Chemie, 2023, v. 135, n. 18, p. 1, doi. 10.1002/ange.202302364
By:
- Teng, Mingxing;
- Jiang, Jie;
- Wang, Eric S.;
- Geng, Qixiang;
- Toenjes, Sean T.;
- Donovan, Katherine A.;
- Mageed, Nada;
- Yue, Hong;
- Nowak, Radosław P.;
- Wang, Jinhua;
- Manz, Theresa D.;
- Fischer, Eric S.;
- Cantley, Lewis C.;
- Gray, Nathanael S.
Publication type:
Article
pSILAC mass spectrometry reveals ZFP91 as IMiD-dependent substrate of the CRL4<sup>CRBN</sup> ubiquitin ligase.
Published in:
Nature Communications, 2017, v. 8, n. 5, p. 15398, doi. 10.1038/ncomms15398
By:
- An, Jian;
- Ponthier, Charles M.;
- Sack, Ragna;
- Seebacher, Jan;
- Stadler, Michael B.;
- Donovan, Katherine A.;
- Fischer, Eric S.
Publication type:
Article
Proteomics‐Based Discovery of First‐in‐Class Chemical Probes for Programmed Cell Death Protein 2 (PDCD2).
Published in:
Angewandte Chemie International Edition, 2023, v. 62, n. 43, p. 1, doi. 10.1002/anie.202308292
By:
- Ji, Wenzhi;
- Byun, Woong Sub;
- Lu, Wenchao;
- Zhu, Xijun;
- Donovan, Katherine A.;
- Dwyer, Brendan G.;
- Che, Jianwei;
- Yuan, Linjie;
- Abulaiti, Xianmixinuer;
- Corsello, Steven M.;
- Fischer, Eric S.;
- Zhang, Tinghu;
- Gray, Nathanael S.
Publication type:
Article
Targeting the Dark Lipid Kinase PIP4K2C with a Potent and Selective Binder and Degrader.
Published in:
Angewandte Chemie International Edition, 2023, v. 62, n. 18, p. 1, doi. 10.1002/anie.202302364
By:
- Teng, Mingxing;
- Jiang, Jie;
- Wang, Eric S.;
- Geng, Qixiang;
- Toenjes, Sean T.;
- Donovan, Katherine A.;
- Mageed, Nada;
- Yue, Hong;
- Nowak, Radosław P.;
- Wang, Jinhua;
- Manz, Theresa D.;
- Fischer, Eric S.;
- Cantley, Lewis C.;
- Gray, Nathanael S.
Publication type:
Article
Discovery of a Potent Degrader for Fibroblast Growth Factor Receptor 1/2.
Published in:
Angewandte Chemie International Edition, 2021, v. 60, n. 29, p. 15905, doi. 10.1002/anie.202101328
By:
- Du, Guangyan;
- Jiang, Jie;
- Wu, Qibiao;
- Henning, Nathaniel J.;
- Donovan, Katherine A.;
- Yue, Hong;
- Che, Jianwei;
- Lu, Wenchao;
- Fischer, Eric S.;
- Bardeesy, Nabeel;
- Zhang, Tinghu;
- Gray, Nathanael S.
Publication type:
Article
Cover Picture: Local Deuteration Enables NMR Observation of Methyl Groups in Proteins from Eukaryotic and Cell‐Free Expression Systems (Angew. Chem. Int. Ed. 25/2021).
Published in:
Angewandte Chemie International Edition, 2021, v. 60, n. 25, p. 13685, doi. 10.1002/anie.202105426
By:
- Dubey, Abhinav;
- Stoyanov, Nikolay;
- Viennet, Thibault;
- Chhabra, Sandeep;
- Elter, Shantha;
- Borggräfe, Jan;
- Viegas, Aldino;
- Nowak, Radosław P.;
- Burdzhiev, Nikola;
- Petrov, Ognyan;
- Fischer, Eric S.;
- Etzkorn, Manuel;
- Gelev, Vladimir;
- Arthanari, Haribabu
Publication type:
Article
Local Deuteration Enables NMR Observation of Methyl Groups in Proteins from Eukaryotic and Cell‐Free Expression Systems.
Published in:
Angewandte Chemie International Edition, 2021, v. 60, n. 25, p. 13783, doi. 10.1002/anie.202016070
By:
- Dubey, Abhinav;
- Stoyanov, Nikolay;
- Viennet, Thibault;
- Chhabra, Sandeep;
- Elter, Shantha;
- Borggräfe, Jan;
- Viegas, Aldino;
- Nowak, Radosław P.;
- Burdzhiev, Nikola;
- Petrov, Ognyan;
- Fischer, Eric S.;
- Etzkorn, Manuel;
- Gelev, Vladimir;
- Arthanari, Haribabu
Publication type:
Article
Mutant‐Selective Allosteric EGFR Degraders are Effective Against a Broad Range of Drug‐Resistant Mutations.
Published in:
Angewandte Chemie International Edition, 2020, v. 59, n. 34, p. 14481, doi. 10.1002/anie.202003500
By:
- Jang, Jaebong;
- To, Ciric;
- De Clercq, Dries J. H.;
- Park, Eunyoung;
- Ponthier, Charles M.;
- Shin, Bo Hee;
- Mushajiang, Mierzhati;
- Nowak, Radosław P.;
- Fischer, Eric S.;
- Eck, Michael J.;
- Jänne, Pasi A.;
- Gray, Nathanael S.
Publication type:
Article
Development of CDK2 and CDK5 Dual Degrader TMX‐2172.
Published in:
Angewandte Chemie International Edition, 2020, v. 59, n. 33, p. 13865, doi. 10.1002/anie.202004087
By:
- Teng, Mingxing;
- Jiang, Jie;
- He, Zhixiang;
- Kwiatkowski, Nicholas P.;
- Donovan, Katherine A.;
- Mills, Caitlin E.;
- Victor, Chiara;
- Hatcher, John M.;
- Fischer, Eric S.;
- Sorger, Peter K.;
- Zhang, Tinghu;
- Gray, Nathanael S.
Publication type:
Article
Development of Dual and Selective Degraders of Cyclin‐Dependent Kinases 4 and 6.
Published in:
Angewandte Chemie International Edition, 2019, v. 58, n. 19, p. 6321, doi. 10.1002/anie.201901336
By:
- Jiang, Baishan;
- Wang, Eric S.;
- Donovan, Katherine A.;
- Liang, Yanke;
- Fischer, Eric S.;
- Zhang, Tinghu;
- Gray, Nathanael S.
Publication type:
Article
Multiomic profiling of breast cancer cells uncovers stress MAPK-associated sensitivity to AKT degradation.
Published in:
Science Signaling, 2024, v. 17, n. 825, p. 1, doi. 10.1126/scisignal.adf2670
By:
- Erickson, Emily C.;
- You, Inchul;
- Perry, Grace;
- Dugourd, Aurelien;
- Donovan, Katherine A.;
- Crafter, Claire;
- Johannes, Jeffrey W.;
- Williamson, Stuart;
- Moss, Jennifer I.;
- Ros, Susana;
- Ziegler, Robert E.;
- Barry, Simon T.;
- Fischer, Eric S.;
- Gray, Nathanael S.;
- Madsen, Ralitsa R.;
- Toker, Alex
Publication type:
Article
Crystal structure of the human COP9 signalosome.
Published in:
Nature, 2014, v. 512, n. 7513, p. 161, doi. 10.1038/nature13566
By:
- Lingaraju, Gondichatnahalli M.;
- Bunker, Richard D.;
- Cavadini, Simone;
- Hess, Daniel;
- Hassiepen, Ulrich;
- Renatus, Martin;
- Fischer, Eric S.;
- Thomä, Nicolas H.
Publication type:
Article
Structure of the DDB1-CRBN E3 ubiquitin ligase in complex with thalidomide.
Published in:
Nature, 2014, v. 512, n. 7512, p. 49, doi. 10.1038/nature13527
By:
- Fischer, Eric S.;
- Böhm, Kerstin;
- Lydeard, John R.;
- Yang, Haidi;
- Stadler, Michael B.;
- Cavadini, Simone;
- Nagel, Jane;
- Serluca, Fabrizio;
- Acker, Vincent;
- Lingaraju, Gondichatnahalli M.;
- Tichkule, Ritesh B.;
- Schebesta, Michael;
- Forrester, William C.;
- Schirle, Markus;
- Hassiepen, Ulrich;
- Ottl, Johannes;
- Hild, Marc;
- Beckwith, Rohan E. J.;
- Harper, J. Wade;
- Jenkins, Jeremy L.
Publication type:
Article
Tubulin Resists Degradation by Cereblon-Recruiting PROTACs.
Published in:
Cells (2073-4409), 2020, v. 9, n. 5, p. 1083, doi. 10.3390/cells9051083
By:
- Gasic, Ivana;
- Groendyke, Brian J.;
- Nowak, Radosław P.;
- Yuan, J. Christine;
- Kalabathula, Joann;
- Fischer, Eric S.;
- Gray, Nathanael S.;
- Mitchison, Timothy J.
Publication type:
Article
Serological testing for SARS-CoV-2 antibodies of employees shows low transmission working in a cancer center.
Published in:
PLoS ONE, 2022, v. 17, n. 4, p. 1, doi. 10.1371/journal.pone.0266791
By:
- Meyerhardt, Jeffrey A.;
- Hong Yue;
- Nowak, Radosław P.;
- Brais, Lauren;
- Chao Ma;
- Johnson, Samantha;
- Harrod, Joanna;
- Burman, Shourya S. Roy;
- Hendrickson, Lynn M.;
- Fischinger, Stephanie;
- Alter, Galit;
- Hahn, William;
- Johnson, Bruce E.;
- Fischer, Eric S.
Publication type:
Article
Discovery and Optimization of Tau Targeted Protein Degraders Enabled by Patient Induced Pluripotent Stem Cells-Derived Neuronal Models of Tauopathy.
Published in:
Frontiers in Cellular Neuroscience, 2022, v. 16, p. 1, doi. 10.3389/fncel.2022.801179
By:
- Catarina Silva, M.;
- Nandi, Ghata;
- Donovan, Katherine A.;
- Cai, Quan;
- Berry, Bethany C.;
- Nowak, Radoslaw P.;
- Fischer, Eric S.;
- Gray, Nathanael S.;
- Ferguson, Fleur M.;
- Haggarty, Stephen J.
Publication type:
Article
Detecting UV-lesions in the genome: The modular CRL4 ubiquitin ligase does it best!
Published in:
FEBS Letters, 2011, v. 585, n. 18, p. 2818, doi. 10.1016/j.febslet.2011.04.064
By:
- Scrima, Andrea;
- Fischer, Eric S.;
- Lingaraju, Gondichatnahalli M.;
- Böhm, Kerstin;
- Cavadini, Simone;
- Thomä, Nicolas H.
Publication type:
Article
Broad-spectrum activity against mosquito-borne flaviviruses achieved by a targeted protein degradation mechanism.
Published in:
Nature Communications, 2024, v. 15, n. 1, p. 1, doi. 10.1038/s41467-024-49161-9
By:
- Liu, Han-Yuan;
- Li, Zhengnian;
- Reindl, Theresia;
- He, Zhixiang;
- Qiu, Xueer;
- Golden, Ryan P.;
- Donovan, Katherine A.;
- Bailey, Adam;
- Fischer, Eric S.;
- Zhang, Tinghu;
- Gray, Nathanael S.;
- Yang, Priscilla L.
Publication type:
Article
From 95 to 59 millimetres: a new active acoustic tag size guideline for salmon.
Published in:
Canadian Journal of Fisheries & Aquatic Sciences, 2021, v. 78, n. 7, p. 943, doi. 10.1139/cjfas-2020-0222
By:
- Liss, Stephanie A.;
- Znotinas, Katherine R.;
- Blackburn, Shannon E.;
- Fischer, Eric S.;
- Hughes, James S.;
- Harnish, Ryan A.;
- Li, Huidong;
- Deng, Zhiqun Daniel
Publication type:
Article

Found: 33