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- Title
Evaluation of residual monomer release and toxicity of self-adhesive resin cements.
- Authors
KURT, Aysegul; ALTINTAS, Subutay Han; KIZILTAS, Mustafa Volkan; TEKKELI, Serife Evrim; GULER, Eray Metin; KOCYIGIT, Abdurrahim; USUMEZ, Aslihan
- Abstract
The aim of this study was to evaluate the amount of leached residual monomers from self-adhesive resin cements and evaluate their toxicity in-vitro. A total of 60 disk-shaped specimens (5 mm in diameter and 0.5 mm in thickness) were prepared from each cement (RelyX U200, SpeedCEM, G-Cem) (n=20). Specimens were immersed in artificial saliva and the amount of released monomers [urethane dimethacrylate (UDMA) and triethyleneglycol dimethacrylate (TEGDMA)] was identified. Then, the cytotoxicity and genotoxicity effect on cells were evaluated using the defined amounts of released monomers from cements. The highest monomer release was detected in G-Cem (p<0.05). The highest cytotoxicity value was identified from SpeedCEM (p<0.01) and the highest genotoxicity values were calculated from RelyX U200 (p<0.05). Released UDMA and TEGDMA from self-adhesive resin cements induced cytotoxicity and genotoxicity effect on cells.
- Subjects
MONOMERS; CEMENT; ARTIFICIAL saliva; GENETIC toxicology; URETHANE
- Publication
Dental Materials Journal, 2018, Vol 37, Issue 1, p40
- ISSN
0287-4547
- Publication type
Article
- DOI
10.4012/dmj.2016-380