We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Contractile responses of uterine smooth muscle to acetylcholine and marihuana extract.
- Authors
Murthy, N.V.A.; Melville, G.N.; Wynter, Hugh H.; Murthy, N V; Wynter, H H
- Abstract
Marihuana extract (ME) is known to influence smooth muscle activity. This study was designed to investigate the effect of crude ME on rat uterine muscle and to explain the mechanism of action using antagonists such as atropine, ergometrine and propranolol. The contractions and the electrical activity were recorded on isolated superfused rat uteri. It is speculated that ME by its uterine stimulatory action compromise uterine blood and may affect oxygen/nutrient transfer. The implication of this to the fetus is discussed.
- Subjects
ACETYLCHOLINE; ANIMAL experimentation; ATROPINE; CANNABIS (Genus); HUMAN reproduction; RATS; SMOOTH muscle; UTERINE contraction; PLANT extracts; PROPRANOLOL; ERGOMETRINE; PHARMACODYNAMICS
- Publication
International Journal of Gynecology & Obstetrics, 1983, Vol 21, Issue 3, p223
- ISSN
0020-7292
- Publication type
journal article
- DOI
10.1016/0020-7292(83)90084-X