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The Neurofilament Surveillance Project (NSP): A biomarker study to sample blood quarterly in familial frontotemporal lobar degeneration.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2022, v. 18, n. 5, p. 1, doi. 10.1002/alz.064959
By:
- Acuna‐Narvaez, Rachel;
- Heuer, Hilary W.;
- Forsberg, Leah K.;
- Alward, Anne;
- Graham, Danielle;
- Fishman, Ann;
- Nelson, Kevin M;
- Kolander, Tyler;
- Fillit, Howard M;
- Galpern, Wendy R;
- Hung, Serena;
- Mason, Chris;
- Mignon, Laurence;
- Ni, Yan G;
- Simen, Arthur;
- Tesseur, Ina;
- Tsai, Richard;
- Yeh, Felix L;
- Mester, Carly T.;
- Ljubenkov, Peter A.
Publication type:
Article
A phase 1 study of AL002 in healthy volunteers.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2021, v. 17, p. 1, doi. 10.1002/alz.054669
By:
- Ward, Michael;
- Long, Hua;
- Schwabe, Tina;
- Rhinn, Herve;
- Tassi, Ilaria;
- Salazar, Santiago Viveros;
- Rychkova, Anna;
- Tu, GuangHuan;
- Barner, Cheryl;
- Yeh, Felix L;
- Spencer, Madeline;
- Paul, Robert
Publication type:
Article
INVOKE‐2: A phase 2 randomized, double‐blind, placebo‐controlled study to evaluate the efficacy and safety of AL002 in participants with early Alzheimer's disease.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2021, v. 17, p. 1, doi. 10.1002/alz.054615
By:
- Paul, Robert;
- Jackson, Sam;
- Ward, Michael;
- Joshi, Aashka;
- Castro, Abraham;
- Yeh, Felix L;
- Liao, Yijie;
- Morrison, Glenn
Publication type:
Article
Six months interim analysis of the phase 2 study of AL001 in frontotemporal dementia patients carrying a granulin mutation.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2021, v. 17, p. 1, doi. 10.1002/alz.054593
By:
- Jackson, Sam;
- Yeh, Felix L;
- Ward, Michael;
- Rhinn, Herve;
- Huang, Julie Y.;
- Pappalardo, Jenna L.;
- Liao, Yijie;
- Hagey, Mackenzie;
- Long, Hua;
- Paul, Robert
Publication type:
Article
AL001 restores CSF PGRN levels and normalizes disease‐associated biomarkers in individuals with frontotemporal dementia due to heterozygous mutations in the progranulin gene: Human: Putative therapeutic results for Alzheimer's and related dementias.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2020, v. 16, n. 11, p. 1, doi. 10.1002/alz.046114
By:
- Haynes, Beth Ann;
- Rhinn, Herve;
- Yeh, Felix L;
- Long, Hua;
- Ward, Michael;
- Hagey, Mackenzie;
- Siddiqui, Omer;
- Paul, Robert
Publication type:
Article
A Phase 1 study of GDC‐0134, a dual leucine zipper kinase inhibitor, in ALS.
Published in:
Annals of Clinical & Translational Neurology, 2022, v. 9, n. 1, p. 50, doi. 10.1002/acn3.51491
By:
- Katz, Jonathan S.;
- Rothstein, Jeffrey D.;
- Cudkowicz, Merit E.;
- Genge, Angela;
- Oskarsson, Björn;
- Hains, Avis B.;
- Chen, Chen;
- Galanter, Joshua;
- Burgess, Braydon L.;
- Cho, William;
- Kerchner, Geoffrey A.;
- Yeh, Felix L.;
- Ghosh, Arundhati Sengupta;
- Cheeti, Sravanthi;
- Brooks, Logan;
- Honigberg, Lee;
- Couch, Jessica A.;
- Rothenberg, Michael E.;
- Brunstein, Flavia;
- Sharma, Khema R.
Publication type:
Article

Found: 6

The Neurofilament Surveillance Project (NSP): A biomarker study to sample blood quarterly in familial frontotemporal lobar degeneration.

A phase 1 study of AL002 in healthy volunteers.

INVOKE‐2: A phase 2 randomized, double‐blind, placebo‐controlled study to evaluate the efficacy and safety of AL002 in participants with early Alzheimer's disease.

Six months interim analysis of the phase 2 study of AL001 in frontotemporal dementia patients carrying a granulin mutation.

AL001 restores CSF PGRN levels and normalizes disease‐associated biomarkers in individuals with frontotemporal dementia due to heterozygous mutations in the progranulin gene: Human: Putative therapeutic results for Alzheimer's and related dementias.

A Phase 1 study of GDC‐0134, a dual leucine zipper kinase inhibitor, in ALS.