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- Title
Laryngeal Carcinoma in Nonsmoking Patients.
- Authors
Hamzany, Yaniv; Hadar, Tuvia; Feinmesser, Raphael; Guttman, Dan; Shvero, Jacob
- Abstract
Objectives: Smoking is a known risk factor for laryngeal carcinoma. We sought to describe the clinicopathologic characteristics and outcomes of nonsmoking patients with laryngeal carcinoma. Methods: Of 1,443 patients treated for laryngeal carcinoma between 1960 and 2006, 55 (3.8%) were nonsmokers: 40 (73%) had never smoked and 15 (27%) had stopped smoking 12 years or more before diagnosis. Patient characteristics and outcomes were reviewed. Results: The study group consisted of 87% men; the mean age at diagnosis was 67 years. All lesions but one were located in the glottis. The 5-year survival rate for the whole group was 85%. Most tumors were detected early. Of 38 patients (69%) with stage Ti disease, there was no significant difference in prognostic features between those who had never smoked and those who had smoked in the past. Conclusions: Fewer than 5% of patients with laryngeal carcinoma were nonsmokers. Like smokers, this subgroup was characterized by a male predominance and an approximate age at diagnosis in the seventh decade. Unlike smokers, non-smokers show a greater predilection for glottic rather than supragiottic disease. There was no difference in prognosis between smokers and nonsmokers, regardless of whether they had smoked in the past.
- Subjects
LARYNGEAL cancer; CANCER diagnosis; CANCER patients; PATIENTS; CIGARETTE smokers
- Publication
Annals of Otology, Rhinology & Laryngology, 2008, Vol 117, Issue 8, p564
- ISSN
0003-4894
- Publication type
Article
- DOI
10.1177/000348940811700802